Bioprocess Engineering

, Volume 18, Issue 6, pp 401–412 | Cite as

Influence of impeller type on power input in fermentation vessels

  • B. H. Junker
  • M. Stanik
  • C. Barna
  • P. Salmon
  • E. Paul
  • B. C. Buckland
Article

Abstract

 Prior investigations comparing radial flow Rushton impellers with axial flow hydrofoil impellers (Maxflo T and A315) were extended at the pilot scale. Six types of impellers (disk-style Rushton, Prochem Maxflo T hydrofoils of three diameters pumping downwards and A315 hydrofoils pumping upwards and downwards) were compared for qualitative differences in power number behavior with Reynolds' number, single versus double impeller power draw, gassed power reduction with aeration number and gas hold-up. Power measurements were obtained using watt transducers which, although limited in accuracy and prone to interferences, were able to provide useful qualitative monitoring results. Measurements were conducted using three model liquid systems: water, glycerol and Melojel (soluble starch). Apparent viscosities for actual Streptomyces cultivations were estimated using measured gassed power values and the experimental relationships obtained for gassed/ungassed power to aeration number and power number to Reynolds' number for the glycerol model system. Results confirmed the lower power number and lower shear environment for hydrofoil impellers, yet suggested useful trends for various process parameters and process fluids.

Keywords

Apparent Viscosity Power Number Fermentation Vessel Aeration Number Power Draw 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • B. H. Junker
    • 1
  • M. Stanik
    • 1
  • C. Barna
    • 2
  • P. Salmon
    • 1
  • E. Paul
    • 1
  • B. C. Buckland
    • 1
  1. 1.Merck Research Laboratories, P.O. Box 2000, Building 810-120, Rahway, NJ, USAUS
  2. 2.Merck Manufacturing Division, West Point, PA, USAUS

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