Biodegradation of tetracycline antibiotics in A/O moving-bed biofilm reactor systems

Research Paper


An anaerobic/aerobic moving-bed biofilm (A/O-MBBR) reactor system was constructed, and the treatment efficiency of aqueous antibiotics in wastewater was investigated. The effects of antibiotics on the microbial communities in the A/O-MBBR were also investigated. Under the optimized reaction conditions, removal of tetracycline antibiotics (TCs) was studied in a series of experiments. When a low concentration of tetracycline (TC) was added to the reactor system, high removal efficiency of conventional pollutants (TC concentration decreased from 10 turn to 2.8 μg L−1) was achieved. When mixed TCs (50 μg L−1) were added to the system, the removal efficiencies of chlortetracycline (CTC), TC and oxytetracycline (OTC) reached 52.03, 41.79, and 38.42%, respectively. TC degradation was decreased to 21.16% when the antibiotic concentration was 500 μg L−1; exposure to this TC concentration destroyed the community structure of the activated sludge bacteria in the reactor. The products of the biodegradation analysis revealed the possible degradation pathways functioning in the experimental A/O-MBBRs.


Anaerobic–oxic Moving-bed biofilm reactor Tetracyclines (TCs) Antibiotics 



The authors gratefully acknowledge the National Natural Science Foundation of China (Project no. 51008216) and the research fund for the Doctoral Program of Higher Education of China (31400347) for their financial support.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.College of Chemistry, Chemical and Environmental EngineeringHenan University of TechnologyZhengzhouPeople’s Republic of China
  2. 2.College of Environmental Science and EngineeringTongji UniversityShanghaiPeople’s Republic of China

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