Biodegradation of tetracycline antibiotics in A/O moving-bed biofilm reactor systems
An anaerobic/aerobic moving-bed biofilm (A/O-MBBR) reactor system was constructed, and the treatment efficiency of aqueous antibiotics in wastewater was investigated. The effects of antibiotics on the microbial communities in the A/O-MBBR were also investigated. Under the optimized reaction conditions, removal of tetracycline antibiotics (TCs) was studied in a series of experiments. When a low concentration of tetracycline (TC) was added to the reactor system, high removal efficiency of conventional pollutants (TC concentration decreased from 10 turn to 2.8 μg L−1) was achieved. When mixed TCs (50 μg L−1) were added to the system, the removal efficiencies of chlortetracycline (CTC), TC and oxytetracycline (OTC) reached 52.03, 41.79, and 38.42%, respectively. TC degradation was decreased to 21.16% when the antibiotic concentration was 500 μg L−1; exposure to this TC concentration destroyed the community structure of the activated sludge bacteria in the reactor. The products of the biodegradation analysis revealed the possible degradation pathways functioning in the experimental A/O-MBBRs.
KeywordsAnaerobic–oxic Moving-bed biofilm reactor Tetracyclines (TCs) Antibiotics
The authors gratefully acknowledge the National Natural Science Foundation of China (Project no. 51008216) and the research fund for the Doctoral Program of Higher Education of China (31400347) for their financial support.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
- 7.Matsuia Y, Ozu T, Inoue T, Matsushia T (2008) Occurrence of a veterinary antibiotic in streams in a small catchment area with livestock farms. Desalination 226(1–3):216–221Google Scholar
- 12.Aba-Guevara CG, Medina-Ramírez IE, Hernández-Ramírez A, Jáuregui-Rincón J, Lozano-Álvarez JA (2017) Comparison of two synthesis methods on the preparation of Fe, N–Co-doped TiO2 materials for degradation of pharmaceutical compounds under visible light. Ceram Int 43(6):5068–5079CrossRefGoogle Scholar
- 13.Zekker I, Rikmann E, Kroon K, Mandel A, Mihkelson J, Tenno T, Tenno T (2017) Ameliorating nitrite inhibition in a low-temperature nitritation–anammox MBBR using bacterial intermediate nitric oxide. Int J Environ Sci Techol 15:1–15Google Scholar
- 17.Chiarello M, Minetto L, Giustina SVD, Beal LL, Moura S (2016) Popular pharmaceutical residues in hospital wastewater: quantification and qualification of degradation products by mass spectroscopy after treatment with membrane bioreactor [J]. Environ Sci Pollut Res 16:1–11Google Scholar
- 22.Plósz BG, Vogelsang C, Macrae K, Heiaas HH, Lopez A, Liltved H, Langford KH (2010) The BIOZO process—a biofilm system combined with ozonation: occurrence of xenobiotic organic micro-pollutants in and removal of polycyclic aromatic hydrocarbons and nitrogen from landfill leachate. Water Sci Technol 61(12):3188–3197CrossRefGoogle Scholar
- 23.Kawan JA, Hasan HA, Suja F, Jaafar O, Abd-Rahman R (2016) A review on sewage treatment and polishing using moving bed bioreactor (MBBR). J Eng Sci Technol 11(8):1098–1120Google Scholar
- 25.Jia RY, Jing DF, Li HX, Xie K, Huang TS, Zhang ZQ, Xu XT, Xia SQ (2011) Membrane bioreactor process for removing selected antibiotics from wastewater at different solids retention times. Fresenius Environ Bull 20(3a):754–763Google Scholar
- 27.Sombatsompop K (2011) A comparative study of sequencing batch rector and moving bed sequencing batch reactor for piggery wastewater treatment. Maejo Int J Sci Technol 5(02):191–203Google Scholar
- 31.Yang YD, Chen DH, Chen L (2010) Studies on characteristics of adsorption and biodegradation of typical PPCPs oxytetracycline in the activated sludge treatment system [J]. Technol Water Treat 36(5):66–69 (in Chinese) Google Scholar