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Bioprocess and Biosystems Engineering

, Volume 36, Issue 3, pp 383–387 | Cite as

Lipase-catalyzed synthesis of hyperbranched poly-l-lactide in an ionic liquid

  • María Mena
  • Alberto López-Luna
  • Keiko Shirai
  • Alberto Tecante
  • Miquel Gimeno
  • Eduardo Bárzana
Short Communication

Abstract

Hyperbranched poly-l-lactides have been synthesized by eROP in [C4MIM][PF6] media. The bis(hydroxymethyl)butyric acid molecule was used as the AB2 core co-monomer and immobilized lipase B from Candida antarctica as biocatalyst. The degree of branching could be controlled by the reaction conditions, with the maximum achieved being 0.21. The successful achievement of the hyperbranched structure is attributed to the high solvent power of substrates and products in the ionic liquid besides sustained lipase activity.

Keywords

Ionic liquids Lipase Hyperbranched polylactide 

Notes

Acknowledgments

We would like to thank PAPIIT IN211412 and CONACyT for the scholarhip (MM) and financial support (funding projects 117503 and 165757).

Supplementary material

449_2012_792_MOESM1_ESM.doc (122 kb)
Supplementary material 1 (DOC 122 kb)

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • María Mena
    • 1
  • Alberto López-Luna
    • 2
  • Keiko Shirai
    • 2
  • Alberto Tecante
    • 1
  • Miquel Gimeno
    • 1
  • Eduardo Bárzana
    • 1
  1. 1.Depto. Alimentos y Biotecnología, Facultad de QuímicaUniversidad Nacional Autónoma de MéxicoMexico DFMexico
  2. 2.Depto. BiotecnologíaUniversidad Autónoma Metropolitana-Unidad IztapalapaMexico DFMexico

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