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Protein tyrosine phosphatase interacting protein 51—a jack-of-all-trades protein

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Abstract

Protein tyrosine phosphatase interacting protein 51 (PTPIP51) interacts both in vitro and in vivo with PTP1B, a protein tyrosine phosphatase involved in cellular regulation. PTPIP51 is known to be expressed in many different types of tissues. It is involved in cellular processes such as proliferation, differentiation and apoptosis. Nevertheless, the exact cellular function of PTPIP51 is still unknown. The present review summarizes our current knowledge of the PTPIP51 gene and its mRNA and protein structure.

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Acknowledgements

We thank the native speaker Mr. Phillip Grant (Department of Differential Psychology and Personality Research, Justus Liebig University, Gießen) for excellent linguistic revision.

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  1. Institute of Anatomy and Cell Biology, Justus-Liebig-University, 35392, Giessen, Germany

    Alexander Brobeil, Manuel Bobrich & Monika Wimmer

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  1. Alexander Brobeil
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  2. Manuel Bobrich
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  3. Monika Wimmer
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Correspondence to Monika Wimmer.

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This paper is dedicated to Prof. Dr. Drs. mult. h.c. Andreas Oksche on the occasion of his 85th birthday.

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Brobeil, A., Bobrich, M. & Wimmer, M. Protein tyrosine phosphatase interacting protein 51—a jack-of-all-trades protein. Cell Tissue Res 344, 189–205 (2011). https://doi.org/10.1007/s00441-011-1146-1

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