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Cell and Tissue Research

, Volume 331, Issue 1, pp 243–250 | Cite as

Neurogenesis in the adult hippocampus

  • Dan EhningerEmail author
  • Gerd Kempermann
Review

Abstract

New neurons continue to be generated in two privileged areas of the adult brain: the dentate gyrus of the hippocampal formation and the olfactory bulb. Adult neurogenesis has been found in all mammals studied to date, including humans. The process of adult neurogenesis encompasses the proliferation of resident neural stem and progenitor cells and their subsequent differentiation, migration, and functional integration into the pre-existing circuitry. This article summarizes recent findings regarding the developmental steps involved in adult hippocampal neurogenesis and the possible functional roles that new hippocampal neurons might play.

Keywords

Neural stem cells Precursor cells Adult neurogenesis Hippocampus Learning and memory 

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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  1. 1.Departments of Neurobiology, Psychology, and Psychiatry and the Brain Research InstituteUniversity of California, Los AngelesLos AngelesUSA
  2. 2.Center for Regenerative Therapies DresdenDresdenGermany

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