A response to “Personalised medicine and population health: breast and ovarian cancer”
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Based on Dr. Narod’s assessment of the premise of personalized medicine in his review “Personalised medicine and population health: breast and ovarian cancer”, we invite him to learn more about the critical studies that are changing the landscape in screening and prevention. As a group of leaders of personalized medicine initiatives in breast cancer, we feel that it is critical to counter Dr. Narod’s pessimistic view of the opportunities for personalizing screening and prevention. In the neoadjuvant breast cancer treatment setting, we are making tremendous strides by understanding and tailoring treatment based on tumor risk, biology, and a better understanding of what can reduce risk using early endpoints. We have the same opportunity to revolutionize breast cancer screening by integrating the concepts of risk stratification, prevention, and early detection. We need an adaptive framework that facilitates continuous learning to maximize benefit, reduce costs, and,...
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