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Human Genetics

, Volume 117, Issue 4, pp 406–407 | Cite as

Genetic Predisposition to Cancer, 2nd edition, by R.A. Eeles, D.F. Easton, B.A.J. Ponder, C. Eng (editors) Arnold, London, 2004, ISBN 0-340-76254-3, hardcover, £ 95.00

  • Ulf Kristoffersson
Book Review
  • 53 Downloads

When I first started to study genetics about 35 years ago, my textbook in human genetics stated that 5% of all human cancers were inherited. I did not reflect very much over this figure, knowing about Warthin’s tumour, von Hippel-Lindau’s disease, familial adenomatous polyposis coli, and some other rare familial cancers. Although I myself later on now and then used this figure in my own teaching, I would not for many years be able to give my students much evidence of its truth, although I stated, as was in the textbook, that the hereditary cases were hidden among the great mass of non-hereditary common cancers. Not until the 1980s when the first hereditary cancer syndromes among the common cancers were delineated, and advances in molecular genetics later on gave the first hints of the complex genetic background, it became evident that really a certain percentage of all cancer was inherited with an autosomal dominant pattern. The first edition of this book, now followed by the second...

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Department of Clinical GeneticsUniversity HospitalLundSweden

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