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Parasitology Research

, Volume 87, Issue 8, pp 609–614 | Cite as

Effect of fasciolicides on the antigenaemia in sheep naturally infected with Fasciola hepatica

  •  R. Sánchez-Andrade
  •  A. Paz-Silva
  •  J. Suárez
  •  R. Panadero
  •  J. Pedreira
  •  P. Díez-Baños
  •  P. Morrondo
Original Paper

Abstract.

A study was developed to evaluate the influence of triclabendazole (Fasinex) and netobimin (Hapasil) the antigenaemia in sheep naturally infected with Fasciola hepatica during 16 weeks. A sandwich-ELISA (enzyme-linked immunosorbent assay) using a rabbit polyclonal IgG antibody to F. hepatica antigens was employed and the data obtained were compared to those from coprological and indirect-ELISA techniques. Triclabendazole reduced the values of circulating antigens at weeks 2–4 post-treatment and faecal output at weeks 2–8 post-treatment, but antibodies showed positive values until the end of the study. Netobimin did not reduce circulating antigens of the trematode nor egg-excretion; and IgG antibodies did not decrease throughout the study.

Keywords

Immunosorbent Assay Faecal Output Triclabendazole Netobimin Hepatica Antigen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  •  R. Sánchez-Andrade
    • 1
  •  A. Paz-Silva
    • 1
  •  J. Suárez
    • 1
  •  R. Panadero
    • 1
  •  J. Pedreira
    • 1
  •  P. Díez-Baños
    • 1
  •  P. Morrondo
    • 1
  1. 1.Departamento de Patología Animal, Parasitología y Enfermedades Parasitarias, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27071 Lugo, Spain

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