Parasitology Research

, Volume 82, Issue 1, pp 90–91 | Cite as

Glycoprotein A is the immunodominant antigen of pneumocystis carinii in mice following immunization

  • Francis Gigliotti
  • Tera McCool
Short Communication


A rapid and simple dual enzyme-linked immunosorbent assay was developed to quantitate the relative frequency of monoclonal antibodies produced against Pneumocystis carinii glycoprotein A (gpA) or other antigens of P. carinii after immunization with whole organisms. In BALB/cj mice, P. carinii gpA was clearly the immunodominant antigen, with a quarter of all hybridomas secreting antibody directed against this molecule.


Mouse Lung Optical Density Public Health Service Grant Immunodominant Antigen Munosorbent Assay 
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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • Francis Gigliotti
    • 1
  • Tera McCool
    • 2
  1. 1.University of Rochester Medical CenterRochesterUSA
  2. 2.University of RochesterRochesterUSA

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