Glycoprotein A is the immunodominant antigen of pneumocystis carinii in mice following immunization
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A rapid and simple dual enzyme-linked immunosorbent assay was developed to quantitate the relative frequency of monoclonal antibodies produced against Pneumocystis carinii glycoprotein A (gpA) or other antigens of P. carinii after immunization with whole organisms. In BALB/cj mice, P. carinii gpA was clearly the immunodominant antigen, with a quarter of all hybridomas secreting antibody directed against this molecule.
KeywordsMouse Lung Optical Density Public Health Service Grant Immunodominant Antigen Munosorbent Assay
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