Advertisement

First report of sparganosis manifested by pleuritis and decreased peripheral blood eosinophils in Jiangsu province, China

  • Kaili Deng
  • Jin Cui
  • Yong Qin
  • Yina Zhu
  • Ganzhu FengEmail author
Helminthology - Short Communication
  • 16 Downloads

Abstract

Sparganosis is a parasitic infection caused by the metacestode stage of Spirometra mansoni and some other related diphyllobothriidean cestodes. Although various internal organs were involved in sparganum infection, pulmonary and pleural involvement is rarely reported. We herein report an uncommon form of sparganosis manifested by pleuritis and decreased peripheral blood eosinophils. Sparganum worms were found in the pleural effusion accidentally and confirmed by pathological diagnosis. After being treated with praziquantel for 10 days, the patient’s symptoms, laboratory examinations, and imaging findings were improved gradually.

Keywords

Spirometra mansoni Sparganosis Pleural effusion P. R. China 

Notes

Acknowledgments

We wish to thank Prof. Yong Wang (Parasitology Department of Nanjing Medical University) for his excellent technical assistance in histological diagnosis.

Funding information

This work is funded by the Natural Sciences Foundation of China (No.81470209).

Compliance with ethical standards

This study was approved by the Medical Ethics Committee of Nanjing Medical University (Nanjing, Jiangsu, China), and all the procedures involving human participants were performed in strict accordance with the 1964 Helsinki declaration and its later amendments.

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent was obtained from all individual participants included in the study.

References

  1. Bracaglia G, Ranno S, Mancinelli L, Santoro M, Cerroni L, Massone C, Sangueza O, Bravo F, Diociaiuti A, Nicastri E, Muraca M, Hachem M, Boldrini R, Callea F, Putignani L (2015) A waterborn zoonotic helminthiasis in an Italian diver: a case report of a cutaneous Sparganum infection and a review of European cases. Pathog Glob Health 109:383–386.  https://doi.org/10.1080/20477724.2015.1123901 CrossRefPubMedPubMedCentralGoogle Scholar
  2. Chen X, Bai J, Wang J, Cheng K, Shen S, Yao H, Tang B, Qian J (2015) Sparganosis presenting as pericardial effusion and lung lesions. Intern Med 54:1135–1139.  https://doi.org/10.2169/internalmedicine.54.3478 CrossRefPubMedGoogle Scholar
  3. Cho SY, Bae JH, Seo BS (1975) Aspects of human sparganosis in Korea. Kisaengchunghak Chapchi 13:60–77PubMedGoogle Scholar
  4. Cui J, Li N, Wang ZQ, Jiang P, Lin XM (2011a) Serodiagnosis of experimental sparganum infections of mice and human sparganosis by ELISA using ES antigens of Spirometra mansoni spargana. Parasitol Res 108:1551–1556CrossRefPubMedGoogle Scholar
  5. Cui J, Lin XM, Zhang HW, Xu BL, Wang ZQ (2011b) Sparganosis, Henan Province, Central China. Emerg Infect Dis 17:146–147CrossRefPubMedPubMedCentralGoogle Scholar
  6. Cui J, Wang Y, Zhang X, Lin XM, Zhang HW, Wang ZQ, Chen JX (2017) A neglected risk for sparganosis: eating live tadpoles in Central China. Infect Dis Poverty 6:58.  https://doi.org/10.1186/s40249-017-0265-7 CrossRefPubMedPubMedCentralGoogle Scholar
  7. Daley Y, Peter T (2015) Inhaled corticosteroids: potency, dose equivalence and therapeutic index. Br J Clin Pharmacol 3(3):372–380CrossRefGoogle Scholar
  8. Fukushima T, Yamane Y (1999) How does the sparganosis occur? Parasitol Today 15:124CrossRefPubMedGoogle Scholar
  9. Ishii H, Mukae H, Inoue Y, Kadota J, Sohno S, Uchiyama F, Nawa Y (2001) A rare case of eosinophilic pleuritis due to sparganosis. Intern Med 40:783–785CrossRefPubMedGoogle Scholar
  10. Li N, Xiang Y, Feng Y, Li M, Gao BL, Li QY (2015) Clinical features of pulmonary sparganosis. Am J Medsci 350:436–441.  https://doi.org/10.1097/MAJ.0000000000000578 CrossRefGoogle Scholar
  11. Liu Q, Li MW, Wang ZD, Zhao GH, Zhu XQ (2015a) Human sparganosis, a neglected food borne zoonosis. Lancet Infect Dis 15:1226–1235.  https://doi.org/10.1016/S1473-3099(15)00133-4 CrossRefPubMedGoogle Scholar
  12. Liu LN, Wang ZQ, Zhang X, Jiang P, Qi X, Liu RD, Zhang ZF, Cui J (2015b) Characterization of Spirometra erinaceieuropaei sparganum cysteine protease and potential application for serodiagnosis of sparganosis. PLoS Negl Trop Dis 9:e0003807CrossRefPubMedPubMedCentralGoogle Scholar
  13. Lu G, Shi DZ, Lu YJ, Wu LX, Li LH, Rao LY, Yin FF (2014) Retrospective epidemiological analysis of sparganosis in mainland China from 1959 to 2012. Epidemiol Infect 142:2654–2661.  https://doi.org/10.1017/S0950268814000144 CrossRefPubMedGoogle Scholar
  14. Ouyang JS, Zhang DQ, Li YP, Chen CS, Li JM (2014) Pleural sparganosis: report of a case and review of the literature. Chin J Tuberc Respir Dis 37(8):601–603 (In Chinese)Google Scholar
  15. Takeda K, Suzuki J, Nagai H, Watanabe K, Yokoyama A, Ando T, Suzuki J, Ohshimab N, Masudaa K, Tamuraa A, Akagawaa S, Kitanic M, Hebisawac A, Matsuia H, Kobayashic N, Maruyamad H, Ohtab K (2016) Thoracoscopic examination of empyema in a patient with sparganosis mansoni. J Infect Chemother 22:120–123.  https://doi.org/10.1016/j.jiac.2015.09.009 CrossRefPubMedGoogle Scholar
  16. Walker MD, Zunt JR (2005) Neuroparasitic infections: cestodes, trematodes, and protozoans. Semin Neurol l25:262–277.  https://doi.org/10.1055/s-2005-917663 CrossRefGoogle Scholar
  17. Zeng QR, He M, Wang F, Zhang ZP, He ZS, Zhou J, Liu BA, Lan ZH, Hu MJ, Cai LT (2012) Pathogen identification of 10 suspected cases of sparganosis mansoni. Chin J Parasitol Parasit Dis 30(224–227):232 (In Chinese)Google Scholar
  18. Zhang X, Wang H, Cui J, Liu LN, Jiang P, Man YX, Zhang ZF, Wang ZQ (2015) Characterization of Spirometra erinaceieuropaei using complete cytb and cox1 genes, and its relationship with Diphyllobothrium species. Infect Genet Evol l35:1–8CrossRefGoogle Scholar
  19. Zhao DJ, Wang YH (2014) Diagnosis and treatment of 6 cases of pulmonary sparganosis. Mod Pract Med 26(1):20–21 (In Chinese)Google Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Kaili Deng
    • 1
  • Jin Cui
    • 1
  • Yong Qin
    • 1
  • Yina Zhu
    • 1
  • Ganzhu Feng
    • 1
    Email author
  1. 1.Department of Respiratory MedicineThe Second Affiliated Hospital of Nanjing Medical UniversityNanjingChina

Personalised recommendations