Disseminated angiostrongylosis with massive cardiac and cerebral involvement in a dog from Italy
- 243 Downloads
A case of disseminated angiostrongylosis caused by Angiostrongylus vasorum in a dog living in Italy is here described. The dog was referred for severe respiratory distress and epileptic seizures; clinicopathological findings were consistent with severe pneumonia associated with right-sided heart failure and multifocal involvement of the brain. Bronchoalveolar fluid analysis identified a multitude of nematode larvae, identified as A. vasorum by conventional and biomolecular (PCR) methods. The major anatomo-histopathological lesions were chronic granulomatous pneumonia, a severe multifocal granulomatous myocarditis and multifocal mild vascular and inflammatory disease in the brain. A. vasorum should be included among the differentials of dogs with cardiovascular and neurologic disease.
KeywordsReference Range Parasitic Burden Severe Respiratory Distress Total Nucleate Cell Nematode Larva
The authors acknowledge Dr. Rossano Maccioni, DVM, for referring the case.
- Altschul SF, Gish W, Miller W, Myers EW (1997) Basic local alignment search tool. J Mol Biol 215:403–410Google Scholar
- Bachellerie JP, Qu LH (1993) Rapid sequencing of parasite rRNA. Meth Mol Biol 21:265–76Google Scholar
- Casewell JL, Williams KJ (2007) Respiratory system. In: Grant Maxie M (ed) Jubb, Kennedy and Palmer's pathology of domestic animals, 5th edn. Saunders, Philadelphia, p 648Google Scholar
- Poli A, Arispici M, Marconcini A, Mancianti F, De Monte D (1984) Angiostrongylus vasorum (Baillet, 1866) in the red fox (Vulpes vulpes) in Italy. J Wildl Dis 20:354–346Google Scholar