Parasitology Research

, Volume 103, Issue 3, pp 713–715 | Cite as

Skin prick test of Kudoa sp. antigens in patients with gastrointestinal and/or allergic symptoms related to fish ingestion

  • Gonzalo Martínez de Velasco
  • Marta Rodero
  • Carmen Cuéllar
  • Tomás Chivato
  • José María Mateos
  • Rafael Laguna
Short Communication

Abstract

A majority of Kudoa spp. infects the somatic muscle of fish establishing cysts. Previously, elevated humoral responses were detected in BALB/c mice immunised with Kudoa sp. pseudocyst extracts and in BALB/c mice orally inoculated with Kudoa sp. pseudocysts, as well as the presence of anti-Kudoa sp. antibodies in human sera by enzyme-linked immunosorbent assay. The objective of this work was to test Kudoa sp. pseudocyst extracts by the skin prick test. Fifteen patients with gastroallergic and/or allergic symptoms related to fish ingestion were examined. Kudoa sp. pseudocyst extracts were administered (1 mg/ml) on the volar forearm skin. Four of the 15 selected patients were positive to Kudoa sp. extracts. The saline solution negative control did not induce any reaction.

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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Gonzalo Martínez de Velasco
    • 1
  • Marta Rodero
    • 1
  • Carmen Cuéllar
    • 1
  • Tomás Chivato
    • 2
  • José María Mateos
    • 2
  • Rafael Laguna
    • 2
  1. 1.Departamento de Parasitología, Facultad de FarmaciaUniversidad ComplutenseMadridSpain
  2. 2.Immunology and Allergy ServiceHospital del AireMadridSpain

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