Parasitology Research

, Volume 99, Issue 6, pp 722–728 | Cite as

Antiparasitic activity of two Lavandula essential oils against Giardia duodenalis, Trichomonas vaginalis and Hexamita inflata

  • Therese Moon
  • Jenny M. Wilkinson
  • Heather M. A. CavanaghEmail author
Original Paper


Two essential oils derived from Lavandula angustifolia and Lavandula × intermedia were investigated for any antiparasitic activity against the human protozoal pathogens Giardia duodenalis and Trichomonas vaginalis and the fish pathogen Hexamita inflata: all of which have significant infection and economic impacts. The study has demonstrated that low (≤1%) concentrations of L. angustifolia and L. × intermedia oil can completely eliminate T. vaginalis, G. duodenalis and H. inflata in vitro. At 0.1% concentration, L. angustifolia oil was found to be slightly more effective than L × intermedia oil against G. duodenalis and H. inflata. The potential applications are discussed.


Giardiasis Nerolidol Antiparasitic Activity Petrin Chenopodium Ambrosioides 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors wish to thank Crestwood Lavender (L. angustifolia) and Forever Lavender (L. × intermedia) for the donation of lavender oils used in this study and to Miss Janelle Wright, Queensland Institute of Medical Research, for advice and technical assistance with this project. This study was funded by a Rural Industries Research and Development Corporation (RIRDC) grant.


  1. Ariana A, Ebadi R, Tahmasebi G (2002) Laboratory evaluation of some plant essences to control Varroa destructor (Acari: Varroidae). Exp Appl Acarol 27(4):319–327CrossRefGoogle Scholar
  2. Athanassopoulo F, Karagouni E, Dostika E, Ragias V, Tavla J, Christofilloyanis P (2004a) Efficacy and toxicity of orally administered anticoccidial drugs for innovative treatments of Polysporoplasma sparis (Sitja-Bobadilla and Alvarez-Pellitero, 1885) infection in Sparus aurata L. J Appl Ichthyol 20:345–354CrossRefGoogle Scholar
  3. Athanassopoulo F, Karagouni E, Dostika E, Ragias V, Tavla J, Christofilloyanis P, Vatsos I (2004b) Efficacy and toxicity of orally administered anticoccidial drugs for innovative treatments of Myxobolus sp. infection in Puntazzo puntazzo. Dis Aquat Org 62:217–226CrossRefGoogle Scholar
  4. Beach MJ, Roberts JM (2000) Giardiasis surveillance—United States 1992–1997. MMWR CDC Surveill Summ 49:1–13Google Scholar
  5. Benoit-Vical F (2005) Ethnomedicine in malaria treatment. Idrugs 8(1):45–52PubMedGoogle Scholar
  6. Biagini G, Rutter A, Finlay B, Lloyd D (1998) Lipids and lipid metabolism in the microaerobic free-living diplomonad Hexamita species. Eur J Protistol 34(2):148–152Google Scholar
  7. Cavanagh HMA, Wilkinson JM (2002) Biological activity of lavender essential oil. Phytother Res 16:301–308PubMedCrossRefGoogle Scholar
  8. Clark CG, Diamond LS (2002) Methods for cultivation of luminal parasitic protists of clinical importance. Clin Microbiol Rev 15:329–341PubMedCrossRefGoogle Scholar
  9. Cudmore SL, Delgaty KL, Hayward-McClelland SF, Petrin DP, Garber GE (2004) Treatment of infections caused by metronidazole-resistant Trichomonas vaginalis. Clin Microbiol Rev 17:783–793PubMedCrossRefGoogle Scholar
  10. Dunne RL, Dunn LA, Upcroft P, O’Donoghue PJ, Upcroft JA (2003) Drug resistance in the sexually transmitted protozoan Trichomonas vaginalis. Cell Res 13(4):239–249PubMedCrossRefGoogle Scholar
  11. Force M, Sparks WS, Ronzio RA (2000) Inhibition of enteric parasites by emulsified oil of oregano in vivo. Phytother Res 14:213–214PubMedCrossRefGoogle Scholar
  12. Hori M (1998) Repellency of rosemary oil against Myzus persicae in a laboratory and in a screenhouse. J Chem Ecol 24:1425–1432CrossRefGoogle Scholar
  13. Ignatowicz S (1997) Powdered herbs of the mint family (Laminaceae) as insect repellants for protection of stored wheat grain. Pol Pis Entomol 66:135–150Google Scholar
  14. Karagouni E, Athanassopoulo F, Lytra A, Komis C, Dotsika E (2005) Antiparasitic and immunomodulatory effect of innovative treatments against Myxobolus sp. infection in Diplodus puntazzo. Vet Parasitol 134:215–228PubMedCrossRefGoogle Scholar
  15. Ketzis JK, Taylor A, Bowman DD, Brown DL, Warnick LD, Erb HN (2002) Chenopodium ambrosioides and its essential oil as treatments for Haemonchus contortus and mixed adult-nematode infections in goats. Small Rumin Res 44(3):193–200CrossRefGoogle Scholar
  16. Leung E (2000) Freshwater aquaristik in focus (online).
  17. Lopes NP, Kato MJ, Andrade EHdeA, Maia JGS, Yoshida M, Planchart AR, Katzin AM (1999) Antimalarial use of volatile oil from leaves of Virola surinamensis (Rol.) Warb. by Waiapi Amazon Indians. J Ethnopharmacol 67:313–319PubMedCrossRefGoogle Scholar
  18. Moon T, Wilkinson JM, Cavanagh HMA (2006) Essential oils from Australian grown Lavandula spp.: a comparison of antibacterial activity. Int J Aromath 16(1):9–14CrossRefGoogle Scholar
  19. O’Brien DJ (1999) Treatment of psoroptic mange with reference to epidemiology and history. Vet Parasitol 83:177–185PubMedCrossRefGoogle Scholar
  20. Patel SR, Wiese W, Patel SC, Ohl C, Byrd JC, Estrada CA (2000) Systematic review of diagnostic tests for vaginal trichomoniasis. Infect Dis Obstet Gynecol 8:248–257PubMedCrossRefGoogle Scholar
  21. Perrucci S, Macchioni G, Cioni PC, Flamini G, Morelli I, Taccini F (1996) The activity of volatile compounds from Lavandula angustifolia against Psoroptes cuniculi. Phytother Res 10:5–8CrossRefGoogle Scholar
  22. Pessoa LM, Morais SM, Bevilaqua CM, Luciano JH (2002) Antihelmintic activity of essential oil of Ocimum gratissimum Linn. and eugenol against Haemonchus contortus. Vet Parasitol 109(1–2):59–63PubMedCrossRefGoogle Scholar
  23. Petrin D, Delgaty K, Bhatt R, Garber G (1998) Clinical and microbiological aspects of Trichomonas vaginalis. Clin Microbiol Rev 11:300–317PubMedGoogle Scholar
  24. Plarre R, Poschko M, Prozell S, Andrea F, Wohlgemuth R, Phillips JK (1997) Effects of oil of cloves and citronellol, two commercially available repellents, against the webbing clothes moth Tineola bisselliella Hum. (Lepidoptera: Tineidae)Anz Schadl.kd Pflanzenschutz Umweltschutz 70:45–50CrossRefGoogle Scholar
  25. Schwebke JR, Burgess D (2004) Trichomoniasis. Clin Microbiol Rev 17:794–803PubMedCrossRefGoogle Scholar
  26. Upcroft J, Upcroft P (1998) My favorite cell: Giardia. Bioessays 20:256–263PubMedCrossRefGoogle Scholar
  27. Upcroft J, Upcroft P (2001) Drug targets and mechanisms of resistance in the anaerobic protozoa. Clin Microbiol Rev 14:150–164PubMedCrossRefGoogle Scholar
  28. Valentin A, Pelissier Y, Benoit F, Marion C, Kone D, Mallie M, Bastide JM, Bessiere JM (1995) Composition and antimalarial activity of volatile components of Lippia multiflora. Phytochemistry 40(5):1442–1493CrossRefGoogle Scholar
  29. Vesy CJ, Peterson WL (1999) The management of giardiasis. Aliment Pharmacol Ther 13:843–850PubMedCrossRefGoogle Scholar
  30. Zenner L, Callait MP, Granier C, Chauve C (2003) In vitro effect of essential oils from Cinnamomum aromaticum, Citrus limon and Allium sativum on two intestinal flagellates of poultry, Tetretrichomonas gallinarum and Histomonas meleagridis. Parasite 10(2):153–157PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Therese Moon
    • 1
  • Jenny M. Wilkinson
    • 1
  • Heather M. A. Cavanagh
    • 1
    Email author
  1. 1.School of Biomedical SciencesCharles Sturt UniversityWagga WaggaAustralia

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