Parasitology Research

, Volume 91, Issue 1, pp 27–33 | Cite as

Parasitological and morphological findings in porcine isosporosis after treatment with symmetrical triazintriones

  • Ute BachEmail author
  • Victoria Kalthoff
  • Hans-Christian Mundt
  • Andreas Popp
  • Matthias Rinke
  • Arwid Daugschies
  • Bernhard Lüttge
Original Paper


Neonatal porcine isosporosis is known to cause serious economic losses in piglet farms by causing severe enteritis with dehydration, weight loss and reduced development in the affected animals, predominantly during the first weeks of life. In the present study, piglets experimentally infected with Isospora suis were treated with Bay Vi 9143, a symmetrical triazintrione, at different days post-infection. As shown by clinical and pathological examinations, Bay Vi 9143 is effective against the asexual and sexual stages of I. suis at all selected treatment times. However, the therapeutic use at an early stage of asexual multiplication is most effective before the onset of clinical symptoms.


Villous Atrophy Parasite Stage Intestinal Villus Fibrinoid Necrosis Sporulated Oocyst 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors wish to thank Petra Hartmann, Alfred Leufgen and Meike Petersen for excellent technical assistance.The animal experiments mentioned in this paper comply with current German laws.


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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • Ute Bach
    • 1
    Email author
  • Victoria Kalthoff
    • 2
  • Hans-Christian Mundt
    • 2
  • Andreas Popp
    • 3
  • Matthias Rinke
    • 3
  • Arwid Daugschies
    • 4
  • Bernhard Lüttge
    • 5
  1. 1.BHC-PH-P-Toxicologic Pathology, Pharma Research CenterBayer AG WuppertalGermany
  2. 2.Animal HealthBayer AG LeverkusenGermany
  3. 3.Pharma Research CenterBayer AGWuppertalGermany
  4. 4.Tierärztliche Hochschule HannoverGermany
  5. 5.Central ResearchBayer AG LeverkusenGermany

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