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Journal of Cancer Research and Clinical Oncology

, Volume 143, Issue 8, pp 1469–1475 | Cite as

Undertreatment trend in elderly lung cancer patients in Brazil

  • Guilherme Jorge Costa
  • Maria Júlia Gonçalves de Mello
  • Carlos Gil Ferreira
  • Luiz Claudio Santos ThulerEmail author
Original Article – Cancer Research

Abstract

Purpose

Elderly patients with lung cancer tend to be undertreated in comparison to younger patients. The objective of this study is to compare treatment modalities offered to lung cancer patients from 70 years of age or more with patients under 70.

Methods

For this study, an analytical cross-sectional epidemiological study conducted with data from the Brazilian hospital-based cancer registries between the years 2000 and 2011. In addition, odds ratios (OR) were calculated, with a 95% confidence intervals (95% CI), in conjunction with the construction of a logistic regression model.

Results

By analyzing the records of 40,403 patients with lung cancer, we found that overall, patients from 70 years of age or more corresponded to 28.6% of the study population. Squamous cell carcinoma was the most common histological type among patients ≥70 years of age, whereas adenocarcinoma was the more prevalent type among younger patients. In comparison to younger patients, the older ones were treated less often (OR = 0.57; 95% CI: 0.52–0.62). Moreover, older patients were less likely to undergo surgery (OR = 0.69; 95% CI: 0.64–0.75), radiotherapy (OR = 0.86; 95% CI: 0.81–0.92), chemotherapy (OR = 0.61; 95% CI: 0.57–0.64), or an association of two or more treatment modalities (OR = 0.58; 95% CI: 0.54–0.62).

Conclusion

The study finds that Brazilian lung cancer patients ≥70 years of age are often undertreated and higher percentage of early death rates as compared to patients under 70. In regard to treatment, age alone should not determine whether patients with lung cancer are treated or not.

Keywords

Lung cancer Elderly patients Undertreatment Brazil 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest regarding the present study.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The internal review board of the Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) approved the study protocol under reference number 3681 in 2013.

Informed consent

For this type of study, informed consent is not required.

Funding

The authors have no funding to report.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Guilherme Jorge Costa
    • 1
  • Maria Júlia Gonçalves de Mello
    • 2
  • Carlos Gil Ferreira
    • 3
  • Luiz Claudio Santos Thuler
    • 4
    Email author
  1. 1.Department of OncologyInstituto de Medicina Integral Prof. Fernando Figueira (IMIP)RecifeBrazil
  2. 2.Hospital Infection Control CommitteeInstituto de Medicina Integral Prof. Fernando Figueira (IMIP)RecifeBrazil
  3. 3.Brazilian Ministry of HealthNational Clinical Cancer Research Network (RNPCC)Rio de JaneiroBrazil
  4. 4.Clinical Research DivisionBrazilian National Cancer Institute (INCA)Rio de JaneiroBrazil

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