Journal of Cancer Research and Clinical Oncology

, Volume 136, Issue 3, pp 379–386

Quality of life among elderly men treated for prostate cancer with either radical prostatectomy or external beam radiation therapy

  • Shunichi Namiki
  • Shigeto Ishidoya
  • Sadafumu Kawamura
  • Tatsuo Tochigi
  • Yoichi Arai
Original Paper

DOI: 10.1007/s00432-009-0665-6

Cite this article as:
Namiki, S., Ishidoya, S., Kawamura, S. et al. J Cancer Res Clin Oncol (2010) 136: 379. doi:10.1007/s00432-009-0665-6

Abstract

Purpose

We evaluated the changes of health-related quality of life (HRQOL) during the first 2 years after radical prostatectomy (RP) or external beam radiation therapy (EBRT) in elderly men (70 years old or older) treated for prostate cancer.

Patients and methods

Between 2002 and 2005, a total of 319 elderly men who underwent RP or EBRT participated in our study. Patients completed the general and disease-specific HRQOL with the Short Form-36 (SF-36) and University of California, Los Angeles Prostate Cancer Index, respectively. The participants were asked to complete the questionnaire before and 3, 6, 12, 18 and 24 months after treatment.

Results

The RP group was younger and had more favorable tumor characteristics than the EBRT group. When compared with the EBRT group, the RP group had higher scores for several SF-36 subscales and sexual function, whereas other domains were comparable. In the EBRT group, there were no significant differences in the general HRQOL scores between the baseline and any of the observation periods. The RP group had a significantly worse urinary function and bother scores postoperatively than the EBRT group. The score for sexual function declined over the 24 months, but more so in the RP group. Similarly, sexual bother scores were significantly lower at each postoperative time point for the RP group.

Conclusions

Both aggressive treatments can offer satisfactory functional outcomes from the perspective of HRQOL for selected elderly subjects with localized prostate cancer.

Keywords

Prostate cancer Quality of life Radical prostatectomy External beam radiation Elderly men 

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Shunichi Namiki
    • 1
    • 2
    • 3
  • Shigeto Ishidoya
    • 1
    • 3
  • Sadafumu Kawamura
    • 1
    • 3
  • Tatsuo Tochigi
    • 1
    • 3
  • Yoichi Arai
    • 1
    • 3
  1. 1.Department of UrologyTohoku University Graduate School of MedicineSendaiJapan
  2. 2.Department of UrologyTohoku University Graduate School of MedicineSendaiJapan
  3. 3.Department of UrologyMiyagi Cancer CenterNatoriJapan

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