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European Journal of Pediatrics

, Volume 156, Issue 5, pp 343–357 | Cite as

A critical appraisal of current management practices for infant regurgitation – recommendations of a working party

  • Y. Vandenplas
  • D. Belli
  • P. Benhamou
  • S. Cadranel
  • J. P. Cezard
  • S. Cucchiara
  • C. Dupont
  • C. Faure
  • F. Gottrand
  • E. Hassall
  • H. Heymans
  • C. M. F. Kneepkens
  • B. Sandhu
REVIEW

Abstract

Regurgitation is a common manifestation in infants below the age of 1 year and a frequent reason of counselling of general practitioners and paediatricians. Current management starts with postural and dietary measures, followed by antacids and prokinetics. Recent issues such as an increased risk of sudden infant death in the prone sleeping position and persistent occult gastro-oesophageal reflux in a subset of infants receiving milk thickeners or thickened “anti-regurgitation formula” challenge the established approach. Therefore, the clinical practices for management of infant regurgitation have been critically evaluated with respect to their efficacy, safety and practical implications. The updated recommendations reached by the working party on the management of infant regurgitation contain five phases: (1A) parental reassurance; (1B) milk-thick ening agents; (2) prokinetics; (3) positional therapy as an adjuvant therapy; (4A) H2-blockers; (4B) proton pump inhibitors; (5) surgery.

Key words Regurgitation   Vomiting   Gastro-oesophageal reflux   Infant   Treatment 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • Y. Vandenplas
    • 1
  • D. Belli
    • 2
  • P. Benhamou
    • 3
  • S. Cadranel
    • 4
  • J. P. Cezard
    • 5
  • S. Cucchiara
    • 6
  • C. Dupont
    • 3
  • C. Faure
    • 5
  • F. Gottrand
    • 7
  • E. Hassall
    • 8
  • H. Heymans
    • 9
  • C. M. F. Kneepkens
    • 10
  • B. Sandhu
    • 11
  1. 1.Academisch Ziekenhuis Kinderen, Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090 Brussels, BelgiumBE
  2. 2.H⊙pital Cantonal, Genève, SwitzerlandCH
  3. 3.H⊙pital Saint Vincent de Paul, Paris, FranceVC
  4. 4.H⊙pital Universitaire d' Enfants Reine Fabiola, Brussels, BelgiumBE
  5. 5.H⊙pital Robert Debrè, Paris, FranceFR
  6. 6.Naples, ItalyIT
  7. 7.H⊙pital C. Huriez, CHU Lille, FranceFR
  8. 8.Children's Hospital, University of British Columbia, Vancouver, CanadaCA
  9. 9.Academisch Medisch Centrum, Amsterdem, The NetherlandsNL
  10. 10.Vrije Universiteit, Amsterdem, The NetherlandsNL
  11. 11.Institute of Child Health, Bristol, Great BritainGB

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