European Journal of Pediatrics

, Volume 156, Issue 4, pp 299–304 | Cite as

Total energy expenditure in infants with bronchopulmonary dysplasia is associated with respiratory status

  • K. de Meer
  • K. R. Westerterp
  • R. H. J. Houwen
  • H. A. A. Brouwers
  • R. Berger
  • A. Okken
NEONATOLOGY

Abstract

Growth failure is a well-known problem in infants with bronchopulmonary dysplasia (BPD). We studied BPD infants' total daily energy expenditure (Ee), nutritional balance, and growth in relation to their past and current clinical status. Applying the doubly labelled water technique, Ee was measured in nine preterm infants with BPD receiving supplemental oxygen (postnatal age 61 ± 13 days) and nine matched controls (36 ± 21 days) during a 6-day period. Energy and protein balance, past and present respiratory status, and growth were assessed as well. The results show that Ee was higher in the BPD infants compared to controls (73 ± 9 vs 63 ± 8 kcal/kg/day, P < 0.05), but their faecal energy loss was lower (P < 0.01). Weight gain, energy intake, energy cost of growth, protein retention, and physical activity were not different. The respiratory frequency (RR) in the BPD infants was elevated in comparison with controls (P < 0.01). Within the BPD group, RR was positively correlated with energy expenditure (regression equation: Ee [kcal/kg/day] = 26.3 + 0.71*RR [min−1]; r2 = 0.82, P < 0.001), and was the single most significant determinant of Ee.

Conclusion Total energy expenditure in BPD infants is elevated and is strongly associated with their respiratory status. These findings could be of practical value for the nutritional management in infants with severe BPD.

Key words Preterm infant   Bronchopulmonary dysplasia   Energy expenditure   Growth   Corticosteroids 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • K. de Meer
    • 1
  • K. R. Westerterp
    • 2
  • R. H. J. Houwen
    • 1
  • H. A. A. Brouwers
    • 1
  • R. Berger
    • 1
  • A. Okken
    • 1
  1. 1.University Children's Hospital `Het Wilhelmina Kinderziekenhuis' P.O. Box 18009, 3501 CA Utrecht, The Netherlands Fax: (31) 30–233–4825NL
  2. 2.Department of Human Biology, University of Limburg Maastricht, The NetherlandsNL

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