European Journal of Pediatrics

, Volume 178, Issue 1, pp 119–120 | Cite as

CPAP support should be considered as the first choice in severe bronchiolitis

  • Alberto Medina
  • Pablo del Villar-GuerraEmail author
  • Vicent Modesto i Alapont


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Beggs S, Wong ZH, Kaul S et al (2014) High-flow nasal cannula therapy for infants with bronchiolitis. Cochrane Database Syst Rev 1:CD009609Google Scholar
  2. 2.
    Bronchiolitis in children: diagnosis and management. NICE guidelines. June 2015Google Scholar
  3. 3.
    Chisti MJ, Salam MA, Smith JH et al (2015) Bubble continuous positive airway pressure for children with severe pneumonia and hypoxaemia in Bangladesh: an open, randomised controlled trial. Lancet 386(9998):1057–1065CrossRefGoogle Scholar
  4. 4.
    Duke T (2014) CPAP: a guide for clinicians in developing countries. Paediatr Int Child Health 34(1):3–11CrossRefGoogle Scholar
  5. 5.
    Ergul AB, Calıskan E, Samsa H, Gokcek I, Kaya A, Zararsiz GE, Torun YA (2018) Using a high-flow nasal cannula provides superior results to OxyMask delivery in moderate to severe bronchiolitis: a randomized controlled study. Eur J Pediatr 177:1299–1307. CrossRefGoogle Scholar
  6. 6.
    Essouri S, Laurent M, Chevret L, Durand P, Ecochard E, Gajdos V, Devictor D, Tissières P (2014) Improved clinical and economic outcomes in severe bronchiolitis with pre-emptive nCPAP ventilatory strategy. Intensive Care Med 40:84–91CrossRefGoogle Scholar
  7. 7.
    Franklin D, Babl FE, Schlapbach LJ, Oakley E, Craig S, Neutze J, Furyk J, Fraser JF, Jones M, Whitty JA, Dalziel SR, Schibler A (2018) A randomized trial of high-flow oxygen therapy in infants with bronchiolitis. N Engl J Med 378:1121–1131CrossRefGoogle Scholar
  8. 8.
    Kepreotes E, Whitehead B, Attia J, Oldmeadow C, Collison A, Searles A, Goddard B, Hilton J, Lee M, Mattes J (2017) High-flow warm humidified oxygen versus standard low-flow nasal cannula oxygen for moderate bronchiolitis (HFWHO RCT): an open, phase 4, randomised controlled trial. Lancet 389(10072):930–939CrossRefGoogle Scholar
  9. 9.
    Machen HE, Mwanza ZV, Brown JK et al (2015) Outcomes of patients with respiratory distress treated with bubble CPAP on a pediatric ward in Malawi. J Trop Pediatr 61(6):421–427Google Scholar
  10. 10.
    Mayfield S, Jauncey-Cooke J, Hough JL et al (2014) High-flow nasal cannula therapy for respiratory support in children. Cochrane Database Syst Rev 3:CD009850Google Scholar
  11. 11.
    Milési C, Essouri S, Pouyau R et al (2017) High flow nasal cannula (HFNC) versus nasal continuous positive airway pressure (nCPAP) for the initial respiratory management of acute viral bronchiolitis in young infants: a multicenter randomized controlled trial (TRAMONTANE study). Intensive Care Med 43(2):209–216CrossRefGoogle Scholar
  12. 12.
    Modesto i Alapont V, Khemani RG, Medina A, Del Villar Guerra P, Molina Cambra A (2017) Bayes to the rescue: continuous positive airway pressure has less mortality than high-flow oxygen. Pediatr Crit Care Med 18(2):e92–e99CrossRefGoogle Scholar
  13. 13.
    Modesto i Alapont V, Garcia Cuscó M, Medina A (2018) High-flow oxygen therapy in infants with bronchiolitis. N Engl J Med 378(25):2444CrossRefGoogle Scholar
  14. 14.
    Walk J, Dinga P, Banda C, Msiska T, Chitsamba E, Chiwayula N, Lufesi N, Mlotha-Mitole R, Costello A, Phiri A, Colbourn T, McCollum ED, Lang HJ (2016) Non-invasive ventilation with bubble CPAP is feasible and improves respiratory physiology in hospitalised Malawian children with acute respiratory failure. Paediatr Int Child Health 36(1):28–33CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Alberto Medina
    • 1
  • Pablo del Villar-Guerra
    • 2
    Email author
  • Vicent Modesto i Alapont
    • 3
  1. 1.Hospital Universitario Central de AsturiasOviedoSpain
  2. 2.Complejo Asistencial de SegoviaSegoviaSpain
  3. 3.Hospital Universitari i Politècnic La FeValenciaSpain

Personalised recommendations