Fitness and academic performance in adolescents. The mediating role of leptin: DADOS study
What is Known:
• Academic performance is associated with physical fitness and leptin concentration in children and adolescents.
• Fitness modulates leptin concentration levels, regardless of physical activity and adiposity.
What is New:
• Leptin concentration mediates the association of cardiorespiratory fitness and muscular strength with academic performance in adolescents.
• Improvements in cardiorespiratory fitness and muscular strength might reduce leptin concentration levels enhancing academic performance.
KeywordsCognition Health School grades Adolescence Leptin
Grade point average
Shuttle run test
MAR was involved in the data collection and analysis, and drafting of the initial manuscript. MRBV was involved in the data collection and critical revision of the manuscript. DJP, JGPG, and OCB were involved in the critical revision of the manuscript. DMU was involved in the study design and data collection, manuscript preparation, and critical revision. All authors have read and approved the final manuscript.
The DADOS Study is funded by the Spanish Ministry of Economy and Competitiveness, MINECO (DEP2013-45515-R) and by the Jaume I University of Castellon, UJI (P1·1A2015-05). This work is partly supported by a Sunny Sport research grant from the Schweppes Suntory Spain Company. DJP was supported by a grant from the Spanish Ministry of Science and Innovation-MINECO (RYC-2014–16938). M.A.R is supported by a Predoctoral Research Grant from UJI (PREDOC/2015/13).
Compliance with ethical statements
Conflict of interest
The authors declare that they have no conflict of interest.
Adolescents and their parents or guardians were informed of the nature and characteristics of the study, and all signed an informed written consent. The DADOS study protocol was designed in accordance with the ethical guidelines of the Declaration of Helsinki 1961 (last revision of Fortaleza, Brazil, 2013) and approved by the Research Ethics Committee of the University Jaume I of Castellon (Spain).
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