European Journal of Pediatrics

, Volume 176, Issue 4, pp 557–557 | Cite as

Prediction of childhood obesity with or without vitamin D deficiency



Obesity Insulin Resistance Adipose Tissue Metabolic Syndrome Plasma Glucose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

With interest, I have read the article by Manios et al. about CORE-index as a screening tool for the early identification of infants that are potentially at higher risk for becoming obese at their childhood and adolescence [3]. I have the following comments.

Childhood obesity is an international public health problem leading to an increased risk of adult obesity and associated with mortality and morbidity [5]. Vitamin D may regulate adipose tissue mass, differentiation, and metabolism in ways that might contribute to overweight and/or obesity possibly by effects on lipogenesis and/or adipogenesis [1]. Vitamin D has been found to be a predictor significantly associated with overweight and/or obesity and other components of metabolic syndrome including raised plasma glucose concentration and insulin resistance [4]. Ekbom et al. [2] reported that higher vitamin D levels were related to a decreased lipid profile in obese children and adolescents.

In this context, considering close association of vitamin D with both childhood obesity and metabolic syndrome parameters, in order to predict childhood obesity, new scoring system including CORE-index and serum vitamin D level might be beneficial.


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Conflict of interest

The author declares that he has no conflict of interest.

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© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Department of PediatricsNear East University HospitalNicosiaCyprus

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