European Journal of Pediatrics

, Volume 176, Issue 4, pp 557–557

Prediction of childhood obesity with or without vitamin D deficiency


DOI: 10.1007/s00431-017-2860-9

Cite this article as:
Cerit, Z. Eur J Pediatr (2017) 176: 557. doi:10.1007/s00431-017-2860-9

With interest, I have read the article by Manios et al. about CORE-index as a screening tool for the early identification of infants that are potentially at higher risk for becoming obese at their childhood and adolescence [3]. I have the following comments.

Childhood obesity is an international public health problem leading to an increased risk of adult obesity and associated with mortality and morbidity [5]. Vitamin D may regulate adipose tissue mass, differentiation, and metabolism in ways that might contribute to overweight and/or obesity possibly by effects on lipogenesis and/or adipogenesis [1]. Vitamin D has been found to be a predictor significantly associated with overweight and/or obesity and other components of metabolic syndrome including raised plasma glucose concentration and insulin resistance [4]. Ekbom et al. [2] reported that higher vitamin D levels were related to a decreased lipid profile in obese children and adolescents.

In this context, considering close association of vitamin D with both childhood obesity and metabolic syndrome parameters, in order to predict childhood obesity, new scoring system including CORE-index and serum vitamin D level might be beneficial.

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Conflict of interest

The author declares that he has no conflict of interest.

Funding statement


Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Department of PediatricsNear East University HospitalNicosiaCyprus

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