European Journal of Pediatrics

, Volume 171, Issue 10, pp 1573–1575 | Cite as

Pressure-induced angioedema associated with endotracheal tube: successful treatment with epinephrine in two cases

  • Çağlar Ödek
  • Tanıl Kendirli
  • Funda Çipe
  • Banu Katlan
  • Figen Doğu
Case Report
First Online:
Received:
Accepted:

Abstract

Pressure-induced urticaria is a non-immunoglobulin E-mediated type of urticaria. Some patients only have angioedema, and the term pressure-induced angioedema (PIA) is more appropriate for them. PIA has not previously been reported in association with endotracheal tube. Here we describe two patients who developed PIA after endotracheal intubation. There were no histories of angioedema, drug and food allergy in both patients. Tests for specific aero-allergens and latex were negative. Serum total immunoglobulin E and C4 levels were in normal ranges. Antihistamines and intravenous steroid therapy were ineffective. Angioedema regressed with intravenous epinephrine infusion and did not relapse after extubation. Conclusion: We suggest that endotracheal tubes can cause PIA. Epinephrine therapy should be used early at treatment, especially in the patients who are at great risk for life-threatening airway problems.

Keywords

Pressure-induced urticaria Angioedema Endotracheal tube Epinephrine Antihistamine 
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Notes

Conflict of interest

The authors state that they have no conflict of interest.

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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Çağlar Ödek
    • 1
  • Tanıl Kendirli
    • 1
  • Funda Çipe
    • 2
  • Banu Katlan
    • 1
  • Figen Doğu
    • 2
  1. 1.Department of Pediatric Critical CareAnkara University Faculty of MedicineAnkaraTurkey
  2. 2.Department of Pediatric Immunology and AllergyAnkara University Faculty of MedicineAnkaraTurkey

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