European Journal of Pediatrics

, Volume 171, Issue 7, pp 1023–1028

Multifocal infantile hepatic hemangiomas—imaging strategy and response to treatment after propranolol and steroids including review of the literature

  • Thangamadhan Bosemani
  • Katherine B. Puttgen
  • Thierry A. G. M. Huisman
  • Aylin Tekes
Original Article

DOI: 10.1007/s00431-011-1671-7

Cite this article as:
Bosemani, T., Puttgen, K.B., Huisman, T.A.G.M. et al. Eur J Pediatr (2012) 171: 1023. doi:10.1007/s00431-011-1671-7

Abstract

Infantile hepatic hemangioma is the most common benign liver tumor during infancy. Prompt diagnosis and timely institution of therapy are of utmost importance. Magnetic resonance imaging (MRI) plays a key role in the correct diagnosis and monitoring of treatment. We report on a 15-week-old girl with multifocal infantile hemangiomas of the liver and high output congestive heart failure. Diagnosis was confirmed by MRI. Subsequent treatment with propranolol and steroids showed dramatic regression of the lesions within 24 weeks. We present the characteristic MRI findings and discuss treatment options together with a comprehensive review of the relevant literature.

Conclusion Propranolol appears highly efficacious in the management of infantile hepatic hemangioma; dedicated MRI is essential in confirming the diagnosis and monitoring of treatment.

Keywords

Infantile hepatic hemangioma Propranolol Steroid Imaging strategy MRI US 

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Thangamadhan Bosemani
    • 1
  • Katherine B. Puttgen
    • 2
  • Thierry A. G. M. Huisman
    • 1
  • Aylin Tekes
    • 1
  1. 1.Division of Pediatric Radiology, Department of Radiology and Radiological ScienceJohns Hopkins HospitalBaltimoreUSA
  2. 2.Division of Pediatric Dermatology, Department of DermatologyJohns Hopkins HospitalBaltimoreUSA

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