European Journal of Pediatrics

, Volume 170, Issue 10, pp 1247–1255 | Cite as

The side effects of phototherapy for neonatal jaundice: what do we know? What should we do?



Neonatal phototherapy (NNPT), a noninvasive, easily available therapy, has been widely used for the treatment of neonatal jaundice for more than half a century. Its efficiency in decreasing plasma bilirubin concentration is well documented, and NNPT leads to greatly reduced exchange transfusion rates for neonates with hyperbilirubinemia. It is generally accepted that the side effects of NNPT are not serious and seem to be well controlled. This review will focus on these possible side effects as well as the approaches to minimize them.


Jaundice Newborn infant Phototherapy Side effect 



This work was supported by grants from National Natural Science Foundation of China (No. 30825039, No. 30973236, and No. 30770748), Ministry of Education of China (IRT 0935; 20070610092), Science and Technology Department of Sichuan Province (No. 2010SZ0280), and Health Department of Sichuan Province (No. 090230).

Conflicts of interest

The authors have no conflicts of interest to disclose.


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Tao Xiong
    • 1
    • 2
  • Yi Qu
    • 1
  • Stephanie Cambier
    • 3
  • Dezhi Mu
    • 1
    • 4
  1. 1.Department of Pediatrics, West China Second University HospitalSichuan UniversityChengduChina
  2. 2.Department of Newborn MedicineAffiliated Hospital of Luzhou Medical CollegeLuzhouChina
  3. 3.Department of PathologyUniversity of CaliforniaSan FranciscoUSA
  4. 4.Department of Neurology, Newborn Brain Research InstituteUniversity of CaliforniaSan FranciscoUSA

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