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European Journal of Pediatrics

, Volume 169, Issue 6, pp 643–650 | Cite as

Clinical practice:

Diagnosis and management of Henoch–Schönlein purpura
  • Hugh J. McCarthy
  • E. Jane Tizard
Review

Abstract

Henoch–Schönlein purpura (HSP) is the most common vasculitis of childhood. In this review, the main clinical features and complications are described. Although most features are self-limiting, renal disease is the most likely to result in long-term morbidity. Treatment of HSP nephritis is controversial, and the evidence for both prevention and treatment of established disease is reviewed. Follow-up for children presenting with HSP should be for at least 6 months and should include regular urine testing for proteinuria and haematuria and a blood pressure measurement. Women with a history of HSP during childhood are at increased risk of complications (such as proteinuria and hypertension) during pregnancy and should be monitored closely. This paper describes current practice with regard to investigation and management and proposes a practical care pathway of the management of a child with HSP.

Keywords

Purpura IgA Glomerulonephritis Intussusception Corticosteroids Treatment 

Notes

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  1. 1.Department of Paediatric NephrologyBristol Royal Hospital for ChildrenBristolUK

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