European Journal of Pediatrics

, Volume 169, Issue 6, pp 767–769 | Cite as

Tick-borne encephalitis presenting as fever without localising signs—a case series

  • Patrick Michael MeyerEmail author
  • Hanspeter Zimmermann
  • Philippe Goetschel
Short Report



Tick-borne encephalitis (TBE) presents without neurologic symptoms in 19% in children less than 16 years in Switzerland (2000–2008). In these cases, fever can be the only leading manifestation.

Case series

We report on four hospitalised children who had TBE and presented as fever without localising signs (FWLS) between 2000 and 2008 in an endemic area in Switzerland.


TBE infection has to be considered in the differential diagnosis of FWLS in endemic areas. Foremost, FWLS characterised by a biphasic fever course and accompanied by headache in patients in a reduced general condition. Affirming that in patients presenting as FWLS also cases of TBE are contained, this disease is underreported.


Tick-borne encephalitis (TBE) Fever without localising signs (FWLS) Children Switzerland 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Patrick Michael Meyer
    • 1
    Email author
  • Hanspeter Zimmermann
    • 2
  • Philippe Goetschel
    • 1
  1. 1.Department of PaediatricsTriemli Hospital ZurichZurichSwitzerland
  2. 2.Division of Communicable DiseasesSwiss Federal Office of Public HealthBernSwitzerland

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