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European Journal of Pediatrics

, Volume 167, Issue 5, pp 549–555 | Cite as

Gastroenteritis by rotavirus in Spanish children. Analysis of the disease burden

  • Francisco Javier Luquero AlcaldeEmail author
  • José María Eiros Bouza
  • Alberto Pérez Rubio
  • Maria Rosario Bachiller Luque
  • José Javier Castrodeza Sanz
  • Raúl Ortiz de Lejarazu Leonardo
Original Paper

Abstract

Rotavirus is one of the most common causes of gastroenteritis worldwide. With the commercialisation of effective rotavirus vaccines in Europe in sight, it is necessary to provide studies which evaluate the disease burden. The aim of this study is two-fold, on one hand, to determine the burden of the rotavirus disease in Spanish children under the age of five, and on the other, to estimate the economic cost of these hospitalizations. The study was undertaken during a 5 year period (2000–2004). The rotavirus hospitalization rate was determined using the Minimum Basic Data Set of the national hospital discharge register. The observed data were compared with those expected by applying a model developed by the Centers for Disease Control and Prevention (CDC) adapted for European Countries. The financial expense of these hospitalizations was estimated. Of all admissions coded as gastroenteritis, 31.6% were due to rotavirus. The hospitalization rate by rotavirus was 480 cases per 100,000 children under five. These data are within the confidence range proposed by the adapted CDC model. The financial expense due to hospitalizations reaches 123,262 euros yearly in a Spanish University Hospital. In conclusion, rotavirus contributes significantly to the hospitalization of acute gastroenteritis. The rate of hospitalization by rotavirus is higher compared to other studies carried out in Spain. In view of future commercialisation of rotavirus vaccines, more in-depth analysis considering direct and indirect costs are necessary.

Keywords

Rotavirus Hospitalisation Disease burden 

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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Francisco Javier Luquero Alcalde
    • 1
    • 4
    Email author
  • José María Eiros Bouza
    • 2
  • Alberto Pérez Rubio
    • 1
  • Maria Rosario Bachiller Luque
    • 3
  • José Javier Castrodeza Sanz
    • 1
  • Raúl Ortiz de Lejarazu Leonardo
    • 2
  1. 1.Servicio de Medicina Preventiva y Salud PúblicaHospital Clínico Universitario de ValladolidValladolidSpain
  2. 2.Sección de VirologíaHospital Clínico Universitario de ValladolidValladolidSpain
  3. 3.Servicio de PediatríaCentro de Salud PilaricaValladolidSpain
  4. 4.C/ Comunidades 2ValladolidSpain

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