European Journal of Pediatrics

, Volume 166, Issue 1, pp 63–65 | Cite as

Cytomegalovirus and Helicobacter pylori co-infection in a child with Ménétrier disease

  • Daisuke Tokuhara
  • Yoshiyuki Okano
  • Kazuyoshi Asou
  • Akiko Tamamori
  • Tsunekazu Yamano
Short Report

Abstract

Ménétrier disease, which is characterized by gastric rugal hypertrophy and hypoproteinemia secondary to a protein-losing gastroenteropathy, is uncommon in childhood. In this report we present the first case of Ménétrier disease in a child with co-infection of cytomegalovirus (CMV) and Helicobacter pylori (H. pylori).

Keywords

Ménétrier disease Helicobacter pylori Cytomegalovirus Protein-losing gastroenteropathy Hypoproteinemia 

Abbreviations

CMV

Cytomegalovirus

H. pylori

Helicobacter pylori

GIE

Gastrointestinal endoscopy

References

  1. 1.
    Bayerdorffer E, Ritter MM, Hatz R, Brooks W, Ruckdeschel G, Stolte M (1994) Healing of protein losing hypertrophic gastropathy by eradication of Helicobacter pylori - is Helicobacter pylori a pathogenic factor in Menetrier’s disease. Gut 35:701–704PubMedGoogle Scholar
  2. 2.
    Occena RO, Taylor SF, Robinson CC, Sokol RJ (1993) Association of Cytomegalovirus with Menetrier’s disease in childhood: Report of two new cases with a review of literature. J Pediatr Gastroenterol Nutr 17:217–224PubMedCrossRefGoogle Scholar
  3. 3.
    Watanabe K, Beinborn M, Nagamatsu S, Ishida H, Takahashi S (2005) Menetrier’s disease in a patient with Helicobacter pylori infection is linked to elevated glucagons-like peptide-2 activity. Scand J Gastroenterol 40:477–481PubMedGoogle Scholar
  4. 4.
    Xiao SY, Hart J (2001) Marked gastric foveolar hyperplasia associated with active cytomegalovirus infection. Am J Gastroenterol 96:223–226PubMedCrossRefGoogle Scholar
  5. 5.
    Yamada M, Sumazaki R, Adachi H, Ahmed T, Matsubara T, Hori T, Nakahara A, Takita H (1997) Resolution of protein-losing hypertrophic gastropathy by eradication of Helicobacter pylori. Eur J Pediatr 156:182–185PubMedCrossRefGoogle Scholar
  6. 6.
    Yasunaga Y, Shinomura Y, Kanayama S, Higashimoto Y, Yabu M, Miyazaki Y, Kondo S, Murayama Y, Nishibayashi H, Kitamura S, Matsuzawa Y (1996) Increased production of interleukin 1 beta and hepatocyte growth factor may contribute to foveolar hyperplasia in enlarged fold gastritis. Gut 39:787–794PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Daisuke Tokuhara
    • 1
  • Yoshiyuki Okano
    • 1
  • Kazuyoshi Asou
    • 1
  • Akiko Tamamori
    • 1
  • Tsunekazu Yamano
    • 1
  1. 1.Department of PediatricsOsaka City University Graduate School of MedicineAbenokuJapan

Personalised recommendations