European Journal of Pediatrics

, Volume 165, Issue 10, pp 688–690 | Cite as

Low prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in a southwestern region of Germany

  • Kirsten Fluegge
  • Brit Adams
  • Urban Luetke Volksbeck
  • Annerose Serr
  • Philipp Henneke
  • Reinhard BernerEmail author
Original Paper



Methicillin-resistant Staphylococcus aureus (MRSA) has developed into an important human pathogen and is increasingly being found to be the cause of skin and soft tissue infections or invasive infections in many communities. We have determined the prevalence of MRSA among S. aureus isolates from pediatric in- and outpatients of the University Children’s Hospital of Freiburg, from children attending primary care pediatricians and from healthy children entering school in a prospective study carried out in a southwestern region of Germany. Of the healthy children tested, all between 5 and 7 years of age, 25.8% were intra-nasally colonized with S. aureus. A total of 1455 S. aureus isolates were tested for antibiotic susceptibility. Apart from penicillin resistance (82.1%), an overall high susceptibility of S. aureus to antibiotics, including clindamycin, was common, while resistance among the S. aureus isolates to erythromycin and clindamycin had even significantly decreased from 2002 to 2004. Methicillin-resistance was exceedingly rare (0.3%).


In the southwestern region of Germany, about one quarter of the healthy children tested at school entry were found to be colonized with S. aureus. The prevalence of MRSA among healthy as well as hospitalized children colonized with S. aureus is still extremely rare in this region.


Staphylococcus aureus Children Germany MRSA Prevalence 



Community-acquired methicillin-resistant Staphylococcus aureus


Hospital-acquired methicillin-resistant Staphylococcus aureus


Methicillin-resistant Staphylococcus aureus



The study was supported by BMBF grant no. 01KI0215 from the Federal Ministry of Education and Research, Germany, to the network

The authors thank Dr. Christian Bogdan (Department of Microbiology and Hygiene, Institute for Medical Microbiology and Hygiene, University Hospital Freiburg) for his critical review of the manuscript.


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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Kirsten Fluegge
    • 1
  • Brit Adams
    • 1
  • Urban Luetke Volksbeck
    • 1
  • Annerose Serr
    • 2
  • Philipp Henneke
    • 1
  • Reinhard Berner
    • 1
    Email author
  1. 1.Department of Pediatrics and Adolescent MedicineUniversity Hospital FreiburgFreiburgGermany
  2. 2.Department of Microbiology and Hygiene, Institute for Medical Microbiology and Hygiene University Hospital FreiburgFreiburgGermany

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