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European Journal of Pediatrics

, Volume 161, Issue 9, pp 491–493 | Cite as

Severe Coxsackie virus B infection in preterm newborns treated with pleconaril

  • Sofia Bauer
  • Giora Gottesman
  • Lea Sirota
  • Ita Litmanovitz
  • Shay Ashkenazi
  • Itzhak Levi
Original Paper

Abstract

Four preterm newborn infants with severe multisystem Coxsackie virus B infection were treated with an oral suspension of pleconaril (5 mg/kg per day). The patients had myocarditis, fulminant hepatitis, meningoencephalitis and disseminated intravascular coagulopathy. All four infants recovered, and no adverse effects of the treatment were noted. Conclusion: pleconaril needs to be comprehensively evaluated in this population.

Coxsackie virus Enterovirus Neonate Pleconaril 

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Copyright information

© Springer-Verlag 2002

Authors and Affiliations

  • Sofia Bauer
    • 1
  • Giora Gottesman
    • 2
  • Lea Sirota
    • 3
  • Ita Litmanovitz
    • 1
  • Shay Ashkenazi
    • 4
  • Itzhak Levi
    • 4
  1. 1.Neonatal Intensive Care Unit, Meir General Hospital, Kfar-Saba, The Sackler School of Medicine, Tel Aviv UniversityIsrael
  2. 2.Paediatric Infectious Diseases, Department of Paediatrics, Meir General Hospital Sapir Medical Centre, Kfar Saba, The Sackler School of Medicine, University of Tel Aviv, 44281Israel
  3. 3.Neonatal Intensive Care Unit, Schneider Children's Medical Centre, Petach Tiva, The Sackler School of Medicine, University of Tel AvivIsrael
  4. 4.Infectious Disease Unit, Schneider Children's Medical Centre, Petach Tiva, The Sackler School of Medicine, University of Tel AvivIsrael

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