Medical Microbiology and Immunology

, Volume 192, Issue 3, pp 137–140 | Cite as

Esophageal cancer in Germany is associated with Epstein-Barr-virus but not with papillomaviruses

  • S. Awerkiew
  • E. Bollschweiler
  • R. Metzger
  • P. M. Schneider
  • A. H. Hölscher
  • H. Pfister
Original Investigation

Abstract.

Esophageal squamous cell carcinomas (n=23) and adenocarcinomas (n=14) from German patients were tested for the presence of human papillomavirus (HPV) and Epstein-Barr-Virus (EBV) DNA. No DNA for either genital HPV or epidermodysplasia verruciformis-associated HPV was detected in any tumor. In contrast, 35% of squamous cell carcinomas and 36% of adenocarcinomas were shown to contain EBV DNA by nested polymerase chain reaction.

Keywords.

Esophageal cancer Human Papillomavirus Epstein-Barr Virus 

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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • S. Awerkiew
    • 1
  • E. Bollschweiler
    • 2
  • R. Metzger
    • 2
  • P. M. Schneider
    • 2
  • A. H. Hölscher
    • 2
  • H. Pfister
    • 1
  1. 1.Institute of Virology, University of Cologne, Fürst-Pückler Str. 56, 50935 Cologne, Germany
  2. 2.Department of Surgery, University of Cologne, Cologne, Germany

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