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Brain Structure and Function

, Volume 224, Issue 2, pp 739–740 | Cite as

Correction to: Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats

  • Shotaro Otsuka
  • Harutoshi SakakimaEmail author
  • Takuto Terashi
  • Seiya Takada
  • Kazuki Nakanishi
  • Kiyoshi KikuchiEmail author
Correction
  • 251 Downloads

Correction to: Brain Structure and Function  https://doi.org/10.1007/s00429-018-1800-4

In the original publication of the article, both the Figs. 2e and 7e have been published incorrectly and the correct Figs. 2 and 7 are given below. The original article has been corrected.

Fig. 2

Preconditioning exercise enhanced the expression of 14-3-3γ in neurons and astrocytes. 14-3-3γ immunoreactivity surrounding the lesion significantly increased in the Ex-only group than in the control group (a, b, n = 6). Representative western blotting and semi-quantitative analysis showed that protein levels of 14-3-3γ significantly increased in the Ex-only group than in the control group (c, d, n = 5 and 4, respectively). The 14-3-3γ positive cells were colocalized with NeuN or GFAP positive cells (e). Date are presented as mean ± SE. *p < 0.05. Scale bar = 50 µm (a) or 20 µm (e)

Fig. 7

The expression of caspase 3 and Bax surrounding the lesion after MCAO. The left side of each photomicrograph (a) shows an ischemic region, and the right side shows a surrounding the lesion (penumbral area). The caspase 3 and Bax immunoreactivities surrounding the lesion were significantly reduced in the Ex group (ac). The caspase 3 immunopositive cells were co-localized with the neuronal marker (NeuN) and astrocyte marker (GFAP) in the Ex group (d), largely observed with the neuronal marker surrounding the lesion. The ratios of survival neurons (arrow) were significantly increased in the Ex group compared to that in the No-Ex group (e). Date are presented as mean ± SE (n = 7). *p < 0.05. Scale bar = 50 µm (a) or 20 µm (d)

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Shotaro Otsuka
    • 1
  • Harutoshi Sakakima
    • 1
    Email author
  • Takuto Terashi
    • 1
  • Seiya Takada
    • 1
  • Kazuki Nakanishi
    • 1
  • Kiyoshi Kikuchi
    • 2
    • 3
    • 4
    • 5
    Email author
  1. 1.Course of Physical Therapy, School of Health Sciences, Faculty of MedicineKagoshima UniversityKagoshimaJapan
  2. 2.Division of Brain Science, Department of PhysiologyKurume University School of MedicineKurumeJapan
  3. 3.Department of NeurosurgeryKurume University School of MedicineKurumeJapan
  4. 4.Department of Systems Biology in ThromboregulationKagoshima University Graduate School of Medical and Dental ScienceKagoshimaJapan
  5. 5.Department of Pharmacology, Faculty of DentistryMahidol UniversityBangkokThailand

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