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Brain Structure and Function

, Volume 219, Issue 3, pp 959–968 | Cite as

The eye of the self: precuneus volume and visual perspective during autobiographical memory retrieval

  • Maxime FretonEmail author
  • Cédric Lemogne
  • Loretxu Bergouignan
  • Pauline Delaveau
  • Stéphane Lehéricy
  • Philippe Fossati
Original Article

Abstract

Visual perspective (i.e. first-person versus third-person perspective) during autobiographical memory (AM) retrieval plays a role in both emotional regulation and self-related processes. However, its neural underpinnings remain mostly unexplored. Visual perspective during AM retrieval was assessed in two independent datasets of 45 and 20 healthy young adults with two different AM retrieval tasks. Diffeomorphic anatomical registration using exponentiated lie algebra and voxel-based morphometry were used to assess individual differences in the precuneus grey matter volume. The spontaneous tendency to recall memories from a first-person perspective was positively correlated with the right precuneus volume among the two independent datasets. Whole-brain analyses revealed that these results were relatively specific to the anterior part of the right precuneus. Our results provide first evidence for the role of the precuneus in egocentric spatial processing in the context of AM retrieval among healthy subjects.

Keywords

Visual perspective Autobiographical memory Precuneus Voxel-based morphometry 

Abbreviations

AM

Autobiographical memory

BDI-13

13-item Beck depression inventory

DARTEL

Diffeomorphic anatomical registration using exponentiated lie algebra

fMRI

Functional magnetic resonance imaging

FWE

Family-wise error

GM

Grey matter

ROI

Region of interest

TIV

Total intracranial volume

VBM

Voxel-based morphometry

Notes

Acknowledgments

M. Freton was supported by fundings from the Foundation pour la Recherche Médicale. C. Lemogne was supported by fundings from the Fonds d’Etude et de Recherche du Corps Médical de l’Assistance Publique-Hôpitaux de Paris and the Lilly Institute. P. Fossati was supported by a NARSAD Young Investigator Award 2003.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Maxime Freton
    • 1
    • 2
    • 3
    Email author
  • Cédric Lemogne
    • 4
    • 5
    • 6
  • Loretxu Bergouignan
    • 7
  • Pauline Delaveau
    • 1
    • 3
  • Stéphane Lehéricy
    • 1
    • 8
    • 9
  • Philippe Fossati
    • 1
    • 2
    • 3
  1. 1.Faculté de MédecineUniversité Pierre et Marie Curie (UPMC)ParisFrance
  2. 2.Assistance Publique-Hôpitaux de Paris, Service de psychiatrie adulte, Bâtiment La Force, Department of PsychiatryHôpital Pitié-SalpêtrièreParis Cedex 13France
  3. 3.CNRS USR 3246Pitié-Salpêtrière HospitalParisFrance
  4. 4.Faculté de Médecine, Sorbonne Paris CitéUniversité Paris DescartesParisFrance
  5. 5.Assistance Publique-Hôpitaux de Paris, Service Universitaire de Psychiatrie de l’adulte et du sujet âgéHôpitaux Universitaires Paris OuestParisFrance
  6. 6.INSERM U894, Centre de Psychiatrie et NeurosciencesHôpital Sainte-AnneParisFrance
  7. 7.Brain, Body and Self Laboratory, Department of NeuroscienceKarolinska InstituteStockholmSweden
  8. 8.CR-ICM, UPMC, INSERM UMRS 975, CNRS 7225, Centre de NeuroImagerie de Recherche (CENIR)Hôpital Pitié-SalpêtrièreParisFrance
  9. 9.Assistance Publique-Hôpitaux de Paris, Department of NeuroradiologyHôpital Pitié-SalpêtrièreParisFrance

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