Non-sebaceous lymphadenoma of the lacrimal gland: first report of a new localization
Tumors of the lacrimal gland are rare, with an incidence of less than 1 per 1,000,000 individuals per year . They represent 6–12% of all orbital space-occupying lesions. Approximately 22–28% of these are primary epithelial tumors [2, 3, 4].
Since lacrimal gland tumors generally recapitulate the clinicopathologic features of their salivary gland counterparts, the World Health Organization (WHO) classification of salivary gland tumors can be applied to these tumors as well .
Fifty percent of primary epithelial tumors of the lacrimal gland are malignant. The most frequently encountered type is adenoid cystic carcinoma, which comprises approximately 20–30% of malignant neoplasms . However, a variety of malignant tumor types that mirror their salivary gland counterparts have been described including ductal carcinoma, acinic cell carcinoma, primary squamous cell carcinoma, mucoepidermoid carcinoma, oncocytic carcinoma, polymorphous low-grade adenocarcinoma, carcinoma...
Compliance with ethical standards
This manuscript is a report of a case with a review of the literature. Research work with human and animal subjects was not conducted in preparation of this manuscript.
Conflict of interest
The authors declare that they have no conflict of interest.
- 5.(2017) Tumours of salivary glands In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (eds) WHO classification of head and neck tumours, 4th edn. IARC, Lyon, pp 159–201Google Scholar
- 7.Font RL, Croxatto JO, Rao NA (2006) Tumours of the lacrimal gland. In: Silverberg SG (ed) Tumours of the eye and ocular adnexa, 4th edn. American Registry of Pathology / Armed Forces Institute of Pathology, Washington DC, pp 223–246Google Scholar
- 9.(2017) Tumours of salivary glands. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (eds) WHO classification of head and neck tumours, 4th edn. IARC, Lyon, pp 190–191Google Scholar
- 14.Weis E, Rootman J, Joly TJ, Berean KW, Al-Katan HM, Pasternak S, Bonavolontà G, Strianese D, Saeed P, Feldman KA, Vangveeravong S, Lapointe JS, White VA (2009) Epithelial lacrimal gland tumors pathologic classification and current understanding. Arch Ophthalmol 127:1016–1028CrossRefPubMedGoogle Scholar