Virchows Archiv

, Volume 455, Issue 3, pp 271–275 | Cite as

Fibroadenoma and intraduct papilloma—a common pathogenesis?

  • Margaret C. Cummings
  • Leonard da Silva
  • David J. Papadimos
  • Sunil R. Lakhani
Case Report


This report describes two cases, each showing fibroepithelial proliferation, admixed with intraduct papillomas. Case 1 was from a 13-year-old female who presented with a breast mass, while case 2 was from a 60-year-old female who also had a breast lump. Case 1 showed proliferative breast disease with multiple small papillomas, some with leaf-like contours. Broad-based parenchymal proliferations protruding into ducts were also seen, and there were overlap features between the two ends of this spectrum. Case 2, similarly, demonstrated a mixed intraductal proliferation, with papillomas on narrow stalks together with low-grade phyllode areas extending into ducts from a wider base. That fibroadenoma and intraduct papilloma may have a common pathogenesis is discussed.


Fibroadenoma Intraduct papilloma Pathogenesis 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Margaret C. Cummings
    • 1
    • 2
  • Leonard da Silva
    • 1
  • David J. Papadimos
    • 4
  • Sunil R. Lakhani
    • 1
    • 2
    • 3
  1. 1.Molecular and Cellular Pathology, Centre for Clinical ResearchUniversity of QueenslandBrisbaneAustralia
  2. 2.Royal Brisbane and Women’s HospitalBrisbaneAustralia
  3. 3.The School of Medicine, University of QueenslandBrisbaneAustralia
  4. 4.Sullivan Nicolaides PathologyBrisbaneAustralia

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