Combined adenosquamous and large-cell neuroendocrine carcinoma of the gallbladder
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Although featuring a relatively simple microscopic anatomy, the gallbladder may give rise to a wide variety of malignant tumors. Beside pure forms of carcinomas, there are different admixed types. We report on a combined adenosquamous and large-cell neuroendocrine carcinoma of the gallbladder, a histological subtype which, to the best of our knowledge, has not been described before.
A 81-year-old female patient was admitted to our hospital with a history of abdominal pain, weight loss, and jaundice for 3 months. At the time of admission, clinical signs of a fracture of the right femoral neck were also present. Cholelithiasis was diagnosed by abdominal ultrasound, whereas conventional radiography of the hip indicated a pathological fracture. The operative findings showed an advanced and unresectable large tumor of the gallbladder with infiltration of the extrahepatic bile ducts and liver. A palliative resection of the tumor with establishment of a biliodigestive...
KeywordsFemoral Head Gallbladder Carcinoma Neuroendocrine Carcinoma Extrahepatic Bile Duct Adenosquamous Carcinoma
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