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Virchows Archiv

, Volume 449, Issue 1, pp 135–136 | Cite as

Combined adenosquamous and large-cell neuroendocrine carcinoma of the gallbladder

  • Aurelia Noske
  • Stefan PahlEmail author
Letter to the Editor

Dear Editor,

Although featuring a relatively simple microscopic anatomy, the gallbladder may give rise to a wide variety of malignant tumors. Beside pure forms of carcinomas, there are different admixed types. We report on a combined adenosquamous and large-cell neuroendocrine carcinoma of the gallbladder, a histological subtype which, to the best of our knowledge, has not been described before.

Case report

A 81-year-old female patient was admitted to our hospital with a history of abdominal pain, weight loss, and jaundice for 3 months. At the time of admission, clinical signs of a fracture of the right femoral neck were also present. Cholelithiasis was diagnosed by abdominal ultrasound, whereas conventional radiography of the hip indicated a pathological fracture. The operative findings showed an advanced and unresectable large tumor of the gallbladder with infiltration of the extrahepatic bile ducts and liver. A palliative resection of the tumor with establishment of a biliodigestive...

Keywords

Femoral Head Gallbladder Carcinoma Neuroendocrine Carcinoma Extrahepatic Bile Duct Adenosquamous Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  1. 1.Institute of PathologyCharité HospitalBerlinGermany

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