Virchows Archiv

, Volume 444, Issue 6, pp 590–593

Pyogenic granuloma: an unrecognized cause of gastrointestinal bleeding

  • Susanne van Eeden
  • G. Johan A. Offerhaus
  • Folkert H. Morsink
  • Bastiaan P. van Rees
  • Olivier R. C. Busch
  • Carel J. M. van Noesel
Case Report

DOI: 10.1007/s00428-004-1013-5

Cite this article as:
van Eeden, S., Offerhaus, G.J.A., Morsink, F.H. et al. Virchows Arch (2004) 444: 590. doi:10.1007/s00428-004-1013-5
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Abstract

Pyogenic granuloma is a lobular capillary hemangioma that mostly occurs on the skin, but it is also encountered on the mucosal surface of the oral cavity. Only a few cases in other parts of the digestive tract have been reported in Japanese patients. In this report, two Caucasian patients are described, who presented with gastrointestinal bleeding due to the presence of a pyogenic granuloma. One was located in the distal esophagus and could be treated with local excision and laser-photocoagulation therapy. The other one was located in the small intestine and was removed by surgical resection. Although extremely rare, pyogenic granuloma as a cause of gastrointestinal bleeding needs consideration. The lesion is benign, presumably reactive and can be adequately treated by excision or laser photocoagulation. Immunohistochemistry and/or polymerase chain reaction for herpesvirus 8 can reliably distinguish pyogenic granuloma from Kaposi’s sarcoma, an important differential diagnosis.

Keywords

Pyogenic granuloma Esophagus Small intestine Gastrointestinal bleeding HHV-8 

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Susanne van Eeden
    • 1
  • G. Johan A. Offerhaus
    • 1
  • Folkert H. Morsink
    • 1
  • Bastiaan P. van Rees
    • 1
  • Olivier R. C. Busch
    • 2
  • Carel J. M. van Noesel
    • 1
  1. 1.Department of PathologyAcademic Medical CenterAmsterdamThe Netherlands
  2. 2.Department of SurgeryAcademic Medical CenterAmsterdamThe Netherlands

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