Virchows Archiv

, Volume 444, Issue 1, pp 13–19

Mucoepidermoid carcinoma of the breast

  • Luca Di Tommaso
  • Maria P. Foschini
  • Teresa Ragazzini
  • Elisabetta Magrini
  • Adele Fornelli
  • Ian O. Ellis
  • Vincenzo Eusebi
Original Article


Five cases of mucoepidermoid carcinoma (MEC) of the breast are reported. All patients were women ranging in age from 29 years to 80 years. As histological grading is one of the most important prognostic factors in breast invasive carcinomas, MEC was graded using the Auclair et al. [1] grading system specific for MEC of salivary glands and the Elston and Ellis [4] grading method, a widely employed grading system in breast cancer. It was found that the two different grading systems appear to be interchangeable in assessing the grade of MEC of the breast. Accordingly, three cases were regarded low grade (G. 1), one intermediate (G. 2) and one high grade (G. 3). The cases were studied with immunohistochemistry and were found to have the same keratin pattern shown by their salivary gland counterpart. It was found that there are more similarities than differences between MEC of the breast and of salivary glands.


Mucoepidermoid carcinoma Breast Salivary glands 


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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Luca Di Tommaso
    • 1
  • Maria P. Foschini
    • 1
  • Teresa Ragazzini
    • 1
  • Elisabetta Magrini
    • 1
  • Adele Fornelli
    • 2
  • Ian O. Ellis
    • 3
  • Vincenzo Eusebi
    • 1
  1. 1.Dipartimento di Scienze Oncologiche, Sezione di Anatomia PatologicaUniversità di Bologna, Ospedale BellariaBolognaItaly
  2. 2.Anatomic PathologyOspedale MaggioreBolognaItaly
  3. 3.Department of HistopathologyCity Hospital NHS TrustNottinghamUnited Kingdom

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