Virchows Archiv

, Volume 441, Issue 5, pp 462–465

Gastric collision between a papillotubular adenocarcinoma and a gastrinoma in a patient with Zollinger-Ellison syndrome

  • Laurence de Leval
  • Noëlle Hardy
  • Manuel Deprez
  • Jean Delwaide
  • Jacques Belaïche
  • Jacques Boniver
Original Article

DOI: 10.1007/s00428-002-0707-9

Cite this article as:
de Leval, L., Hardy, N., Deprez, M. et al. Virchows Arch (2002) 441: 462. doi:10.1007/s00428-002-0707-9

Abstract.

We report a unique case of a gastric collision tumor composed of an intramural gastrin-secreting tumor and a papillotubular adenocarcinoma of the intestinal type discovered at autopsy in a patient with Zollinger-Ellison syndrome. There was extensive metastatic dissemination of the neuroendocrine component to regional lymph nodes and to the liver. The unusual macroscopical, histological, and immunohistochemical features of this case and its specific clinical setting are discussed

Carcinoma-carcinoid spectrum Gastric collision tumor Intramural gastrin-secreting tumor Papillotubular adenocarcinoma Zollinger-Ellison syndrome 

Copyright information

© Springer-Verlag 2002

Authors and Affiliations

  • Laurence de Leval
    • 1
  • Noëlle Hardy
    • 1
  • Manuel Deprez
    • 1
  • Jean Delwaide
    • 2
  • Jacques Belaïche
    • 2
  • Jacques Boniver
    • 1
  1. 1.Department of Pathology, CHU of Liège, Sart-Tilman, 4000 Liège, Belgium
  2. 2.Department of Gastroenterology, CHU of Liège, Sart-Tilman, 4000 Liège, Belgium

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