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ParaHox gene expression in the polychaete annelid Capitella sp. I

  • Andreas C. Fröbius
  • Elaine C. SeaverEmail author
Original Article

Abstract

Hox and ParaHox genes are transcriptional regulators vital for many aspects of embryonic development in bilaterian animals and are considered to have originated from one ancestral proto-Hox/ParaHox cluster. Hox genes are clustered in the genome of both protostomes and deuterostomes, and there is a specific relationship between the position of a gene in the cluster and the position of its expression along the animal body axis (colinearity). It is not clear whether the ParaHox genes Gsx, Xlox, and, Cdx generally exhibit a similar phenomenon since developmental expression for all three ParaHox genes within a single species has not yet been described for any protostome animal. Here we show the spatial and temporal localization for all three ParaHox genes in the polychaete Capitella sp. I, a member of one of the morphologically most diverse and understudied groups within the Metazoa, the Lophotrochozoa. Our data demonstrate that although both CapI-Xlox and CapI-Cdx are regionally expressed in the gut, the three Capitella sp. I ParaHox genes as a group do not perfectly fit predictions of temporal or spatial colinearity. Instead, there is a conservation of expression across species associated with development of particular tissues, and the relative order of initiation of ParaHox gene expression likely reflects the relative order of species-specific tissue development during ontogenesis.

Keywords

ParaHox Gut Capitella sp. I Gsx Xlox Cdx 

Notes

Acknowledgements

This work was supported by NSF (IBN00-94925). We are grateful to members of Kewalo Marine Lab for discussions and comments on the preparation of this manuscript.

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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  1. 1.Kewalo Marine LabPBRC/University of HawaiiHonoluluUSA
  2. 2.Institut für Phytopathologie und Angewandte ZoologieJustus-Liebig-Universität GießenGiessenGermany

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