Analysis of Fz10 expression in mouse embryos
Expression Note
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Abstract
Wnt signaling molecules regulate the development of multiple organs in vertebrate embryos. We have isolated cDNA clones for frizzled10 (Fz10), which encodes a putative Wnt receptor, to further characterize the mechanisms of Wnt signaling in mouse embryos. Interestingly, Fz10 is expressed in the same regions as Wnt7a in the neural tube, limb buds, and Müllerian duct.
Keywords
frizzled Limb development Müllerian ductNotes
Acknowledgements
We thank Kari McDonald for help with the initial characterization of the Fz10 clone. A.P.N. was supported by N.I.H. training grant GM07135 to the MCD Biology Department at the University of Colorado.
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