Planta

, Volume 214, Issue 3, pp 345–355

Multifunctionality of plant ABC transporters – more than just detoxifiers

  • Enrico Martinoia
  • Markus Klein
  • Markus Geisler
  • Lucien Bovet
  • Cyrille Forestier
  • Üner Kolukisaoglu
  • Bernd Müller-Röber
  • Burkhard Schulz
Review

DOI: 10.1007/s004250100661

Cite this article as:
Martinoia, E., Klein, M., Geisler, M. et al. Planta (2002) 214: 345. doi:10.1007/s004250100661

Abstract.

The ABC-transporter superfamily is one of the largest protein families, and members can be found in bacteria, fungi, plants and animals. The first reports on plant ABC transporters showed that they are implicated in detoxification processes. The recent completion of the genomic sequencing of Arabidopsis thaliana (L.) Heynh. [Arabidopsis Genome Initiative (2000) Nature 408:796–815] showed that Arabidopsis contains more than 100 ABC-type proteins; 53 genes code for so-called full-size transporters, which are large proteins of about 150 kDa consisting of two hydrophobic and two hydrophilic domains. The large number of genes in the MDR/MRP and PDR5-like sub-clusters and the strong sequence homology found in many cases suggest functional redundancy. One reason for the high number of genes can be attributed to the duplication of large segments of Arabidopsis chromosomes. Recent results indicate that the function of this protein family is not restricted to detoxification processes. Plant ABC transporters have been demonstrated to participate in chlorophyll biosynthesis, formation of Fe/S clusters, stomatal movement, and probably ion fluxes; hence they may play a central role in plant growth and developmental processes.

ABC transporter Arabidopsis (ABC transporters) Detoxification Gene inventory 

Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • Enrico Martinoia
    • 1
  • Markus Klein
    • 1
  • Markus Geisler
    • 1
  • Lucien Bovet
    • 1
  • Cyrille Forestier
    • 2
  • Üner Kolukisaoglu
    • 3
  • Bernd Müller-Röber
    • 4
  • Burkhard Schulz
    • 5
  1. 1.Institut de Botanique, Laboratoire de Physiologie Végétale, Université de Neuchâtel, Rue Emile Argand 13, 2007 NeuchâtelSwitzerland
  2. 2.CEA-CEN Cadarache, DEVM-LEMS, BP 1, 13108 St Paul Lez DuranceFrance
  3. 3.Institut für Pflanzenphysiologie, Universität Rostock, Doberaner Strasse 143, 18051 RostockGermany
  4. 4.Max-Planck-Institut für Molekulare Pflanzenphysiologie (MPI-MP), 14424 PotsdamGermany
  5. 5.Botanisches Institut II, Universität zu Köln, Max-Delbrück-Laboratorium in der Max-Planck-Gesellschaft, Carl-von-Linné-Weg 10, 50829 KölnGermany

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