Bio-solar cell factories for photosynthetic isoprenoids production
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Photosynthetic production of isoprenoids in cyanobacteria is considered in terms of metabolic engineering and biological importance.
Metabolic engineering of photosynthetic bacteria (cyanobacteria) has been performed to construct bio-solar cell factories that convert carbon dioxide to various value-added chemicals. Isoprenoids, which are found in nature and range from essential cell components to defensive molecules, have great value in cosmetics, pharmaceutics, and biofuels. In this review, we summarize the recent engineering of cyanobacteria for photosynthetic isoprenoids production as well as carbon molar basis comparisons with heterotrophic isoprenoids production in engineered Escherichia coli.
KeywordsIsoprenoid Terpene CO2 conversion Cyanobacteria Metabolic engineering
Dry cell weight
- PCC 6803
Synechocystis sp. PCC 6803
- PCC 7942
Synechococcus elongatus PCC 7942
- PCC 7120
Anabaena sp. PCC 7120
- PCC 7002
Synechococcus sp. PCC 7002
The authors thank Prof. Sang Jun Sim at Korea University and Prof. EonSon Jin at Hanyang University for valuable discussion.
This work was supported by Korea CCS R&D Center (KCRC) (2017M1A8A1072034) and Basic Science Research Program (2017R1A2B2002566) through the National Research Foundation of Korea, funded by the Korean Government (Ministry of Science and ICT). In addition, this work was partially supported by the Golden Seed Project (213008-05-1-WT911) grant, funded by the Ministry of Agriculture and the Ministry of Oceans and Fisheries.
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Conflict of interest
The authors declare that they have no conflict of interest.
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