The role of GRAS proteins in plant signal transduction and development
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GRAS proteins are a recently discovered family of plant-specific proteins named after GAI, RGA and SCR, the first three of its members isolated. Although the Arabidopsis genome encodes at least 33 GRAS protein family members only a few GRAS proteins have been characterized so far. However, it is becoming clear that GRAS proteins exert important roles in very diverse processes such as signal transduction, meristem maintenance and development. Here we present a survey of the different GRAS proteins and review the current knowledge of the function of individual members of this protein family.
KeywordsArabidopsis DELLA proteins Development GRAS proteins Protein family Signal transduction
I thank Reinhold G. Herrmann, Randy Foster and the members of the group for useful discussion and critical reading of the manuscript. I am grateful to Nam-Hai Chua for support during the first stages of this project. My thanks to Philip Benfey for sharing information before publication. I apologize to those colleagues whose work was not cited because of space limitations. Work in my laboratory is supported by the Deutsche Forschungsgemeinschaft (DFG) and the Arabidopsis Functional Genomics Network (AFGN, grant no. BO 1146/4-1 to C.B.).
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