Transient receptor potential channelopathies

Molecular and Genomic Physiology

Abstract

In the past years, several hereditary diseases caused by defects in transient receptor potential channels (TRP) genes have been described. This review summarizes our current knowledge about TRP channelopathies and their possible pathomechanisms. Based on available genetic indications, we will also describe several putative pathological conditions in which (mal)function of TRP channels could be anticipated.

Keywords

TRP channels Channelopathies Drug targets Hereditary diseases SNP Cation channel Calcium signalling Calcium Magnesium 

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© Springer-Verlag 2010

Authors and Affiliations

  1. 1.Laboratory Ion Channel Research, Department of Molecular Cell BiologyKU LeuvenLeuvenBelgium

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