Langenbeck's Archives of Surgery

, Volume 401, Issue 2, pp 133–140

German recommendations for pretransplantation donor kidney biopsies

  • Przemyslav Pisarski
  • Christina Schleicher
  • Ingeborg Hauser
  • Jan U. Becker
REVIEW ARTICLE
  • 141 Downloads

Abstract

Purpose

This manuscript reviews the data about the histopathologic and develops recommendations to standardise and improve the biopsy procedure, the biopsy handling, the histopathological evaluation, the communication of results and the collection of data from pretransplantation kidney biopsies of deceased donors in Germany.

Methods

The recommendations are based on this literature review, on discussions at two workshops held by the German Society of Pathology and the German Organ Transplantation Foundation and on personal experiences of the authors.

Results

These German recommendations advocate the use of punch biopsies, paraffin embedding and detailed descriptive reporting of histopathological findings.

Conclusions

These recommendations constitute only a starting point. Periodical revisions will help to simplify and optimise the recommendations with the ultimate goal to prospectively gather data for the elaboration of a computer-based algorithm that allows the exact prediction of transplantation outcome for a given match of donor and recipient.

Keywords

Preimplantation biopsy Zero-hour biopsy Preimplant biopsy Preimplantation biopsy Donor biopsy 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Przemyslav Pisarski
    • 1
  • Christina Schleicher
    • 2
  • Ingeborg Hauser
    • 3
  • Jan U. Becker
    • 4
  1. 1.Department of General and Visceral SurgeryUniversity Hospital FreiburgFreiburgGermany
  2. 2.German Organ Transplantation FoundationFrankfurtGermany
  3. 3.Medical Clinic III, NephrologyUniversity Hospital FrankfurtFrankfurtGermany
  4. 4.Institute of PathologyUniversity Hospital of CologneCologneGermany

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