Surgery for liver metastases originating from sarcoma—case series
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Liver metastases originating from various types of sarcoma are a rare reason for hepatic resection. So far, even multicentre studies do hardly provide statistically relevant sample sizes. Thus, review of available data can provide surgeons with useful information in similar cases. Therefore, this study can be regarded more as a contribution to this pool of data than as a stand-alone paper.
Patients and methods
The study includes 10 women and five men who underwent subtotal hepatic resection for solitary (n = 4) and multiple (n = 11) liver metastases originating from sarcoma. The median tumour diameter was 60 mm (range 20–200 mm).
Morbidity was 33%. One patient died within 30 days after surgery. Resection was complete (R0) in 67%. Median overall survival was 33.6 months, 5-year survival 27%. The use of Pringle manoeuvre was significantly associated with poorer outcome (p = 0.014) and shorter period of recurrence-free survival (p = 0.012). Diameter of liver lesion over 50 mm showed significantly shorter recurrence-free survival (p = 0.042).
Hepatic resection may be beneficial in patients with isolated sarcoma metastasis in the liver.
KeywordsLiver Metastasis Sarcoma Hepatectomy
The authors thank Rene Adam, M.D. and Javier C Lendoire, M.D. for their review of Table 3 and Eugenia Lamont for proofreading the manuscript.
Conflicts of interest
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