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European Journal of Applied Physiology

, Volume 85, Issue 1–2, pp 151–156 | Cite as

Exercise-induced changes in blood levels of α-tocopherol

  •  M. Hütler
  •  S. Woweries
  •  R. Leithäuser
  •  D. Böning
  •  R. Beneke
Original Article

Abstract.

Levels of α-tocopherol (αT) in plasma and red blood cells (RBC) are assumed to be modulated by exercise. The mechanisms involved remain to be established. We examined the influence of different running bouts on the content of αT in RBC (αTRBC), the concentration in plasma (αTplasma), and their relationship with lipolysis, as indicated by changes (Δ) in plasma glycerol concentration ([glycerol]). Eleven healthy runners [mean (SD) age 35 (9) years, height 177.3 (7.6) cm, body mass 69.6 (9.4) kg, and peak oxygen consumption, \(\dot V{\rm O}_{{\rm 2peak}} \) , 57.8 (4.8) ml.kg–1.min–1] performed an incremental treadmill test [duration 17 (2) min, peak velocity, v peak 4.8 (0.4) m.s–1], a training run [173 (12) min, 57 (4)% v peak] and a marathon [197 (24) min, 75 (5)% v peak]. Before (pre) and after (post) each run, haematological and lipid parameters, αTRBC and αTPlasma were determined. Haemoconcentration was observed after each run. Δ[glycerol] was +0.10 (0.10) mmol.l–1, +0.40 (0.14) mmol.l–1 and +0.51 (0.15) mmol.l–1 in the treadmill test, training run and marathon, respectively. When corrected for haemoconcentration, values of αTplasma decreased [–5.4 (7.5)%, P<0.05] in the treadmill test, were unchanged [+0.7 (8.7)%] in the training run and increased [+7.8 (8.3)%, P<0.05] in the marathon. αTRBC decreased [pre vs post: 22.7 (3.2) nmol.g haemoglobin–1 (nmol.g Hb–1) vs 18.9 (3.8) nmol.g Hb–1, P<0.05] in the treadmill test and was not significantly changed in either the training run [20.8 (1.9) nmol.g Hb–1 vs 19.1 (3.0) nmol.g Hb–1] or the marathon [21.6 (2.9) nmol.g Hb–1 vs 23.4 (2.7) nmol.g Hb–1]. ΔαTRBC and ΔαTplasma were positively related to Δ[glycerol]. The reduction in αTRBC and αTplasma after short-lasting heavy exercise indicates the consumption of αT, whereas the association between ΔαT and Δ[glycerol] suggests mobilisation of αT, especially in long-lasting exercises. However, although αT appears to be influenced by exercise, the results suggest a well-balanced regulation of αT during exercise resulting in small, and only in part, significant ΔαT in blood.

Vitamin E Triglyceride-fatty acid cycle Antioxidant Red blood cell 

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Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  •  M. Hütler
    • 1
  •  S. Woweries
    • 1
  •  R. Leithäuser
    • 2
  •  D. Böning
    • 1
  •  R. Beneke
    • 1
  1. 1.Department of Sports Medicine, University Hospital Benjamin Franklin, Free University Berlin, Clayallee 229, Berlin 14195, Germany
  2. 2.LMC Laboratory, Berlin, Mecklenburgische Straße 28, Berlin 14197, Germany

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