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European Journal of Applied Physiology

, Volume 119, Issue 2, pp 441–453 | Cite as

Ventilatory responses in males and females during graded exercise with and without thoracic load carriage

  • Devin B. PhillipsEmail author
  • Cameron M. Ehnes
  • Michael K. Stickland
  • Stewart R. Petersen
Original Article

Abstract

Purpose and methods

To compare the effects of thoracic load carriage on the ventilatory and perceptual responses to graded exercise, 14 pairs of height-matched, physically active males and females completed randomly ordered modified Balke treadmill exercise tests with and without a correctly sized and fitted 20.4 kg backpack and work clothing. Subjects walked at 1.56 m.s− 1 while grade was increased by 2% every 2 min until exhaustion. Ventilatory responses were measured with open circuit spirometry and perceptual responses were evaluated using the modified Borg scale. Inspiratory capacity maneuvers were performed to calculate operating lung volumes.

Results

Despite height matching, males had significantly greater lung volumes and peak oxygen uptake (\(\dot {V}\)O2peak). Peak \(\dot {V}\)O2 and ventilation (\(\dot {V}\)E) were lower (p < 0.05) for all subjects under load. Throughout exercise, the ventilatory equivalents for \(\dot {V}\)O2 and carbon dioxide production were significantly higher in females, independent of condition. At similar relative submaximal intensities (%\(\dot {V}\)O2peak), there was no difference in \(\dot {V}\)E between conditions in either group, however, all subjects adopted a rapid and shallow breathing pattern under load with decreased tidal volume secondary to lower end-inspiratory lung volume. The relative changes in breathing pattern and operating lung volume between unloaded and loaded conditions were similar between males and females. Females reported significantly higher dyspnea ratings for a given \(\dot {V}\)E compared to males; however, the relationship between dyspnea and \(\dot {V}\)E was unaffected by load carriage.

Conclusion

The relative response patterns for ventilatory and perceptual responses to graded exercise with thoracic loading were similar in males and females.

Keywords

Thoracic load carriage Occupational physiology Sex differences Ventilation Operating lung volume Oxygen uptake 

Abbreviations

ANOVA

Analysis of variance

fB

Breathing frequency

EELV

End-expiratory lung volume

EILV

End-inspiratory lung volume

FEV1

Forced expired volume in 1 s

FVC

Forced vital capacity

IC

Inspiratory capacity

METS

Metabolic equivalent

PaCO2

Partial pressure of arterial carbon dioxide

PEFR

Peak expiratory flow rate

PETCO2

Partial pressure of end-tidal carbon dioxide

RER

Respiratory exchange ratio

\(\dot {V}\)CO2

Carbon dioxide production

\(\dot {V}\)E

Minute ventilation

\(\dot {V}\)O2

Oxygen consumption

VT

Tidal volume

Notes

Acknowledgements

Technical assistance from Bradley Welch is acknowledged.

Author contributions

DBP, MKS and SRP conceived and designed the experiment. DBP, CME and SRP conducted experiments. DBP, CME, MKS and SRP analyzed and interpreted data. DBP and SRP wrote the manuscript. All authors read and approved the manuscript.

Compliance with ethical standards

Conflict of interest

There are no conflicts of interest.

References

  1. Åstrand P-O, Rodahl K (1986) Textbook of work physiology. Physiological bases of exercise, 3rd edn. McGraw Hill, New YorkGoogle Scholar
  2. Borg GAV (1982) Psychophysical bases of perceived exertion. Med Sci Sports Exerc 14(5):377–381CrossRefGoogle Scholar
  3. Bouwsema MM, Tedjasaputra V, Stickland MK (2017) Are there sex differences in the capillary blood volume and diffusing capacity response to exercise? J Appl Physiol 122(3):460–469CrossRefGoogle Scholar
  4. Dominelli PB, Sheel AW, Foster GE (2012) Effect of carrying a weighted backpack on lung mechanics during treadmill walking in healthy men. Eur J Appl Physiol 112(6):2001–2012CrossRefGoogle Scholar
  5. Dominelli PB, Molgat-Seon Y, Bingham D, Swartz PM, Road JD, Foster GE, Sheel AW (2015a) Dysanapsis and the resistive work of breathing during exercise in healthy men and women. J Appl Physiol (1985) 119(10):1105–1113CrossRefGoogle Scholar
  6. Dominelli PB, Render JN, Molgat-Seon Y, Foster GE, Romer LM, Sheel AW (2015b) Oxygen cost of exercise hyperpnoea is greater in women compared with men. J Physiol 593(8):1965–1979CrossRefGoogle Scholar
  7. Dominelli PB, Ripoll JG, Cross TJ, Baker SE, Wiggins CC, Welch BT, Joyner MJ (2018) Sex-differences in large conducting airway anatomy. J Appl Physiol 215(3):960–965CrossRefGoogle Scholar
  8. Eid E (2001) Challenges posed by the Supreme Court of Canada in the Meiorin Decision to employers in physically demanding occupations. In: Gledhill N, Bonneau J, Salmon A (eds) Bona fide occupational requirements. Proceedings of the consensus forum on establishing bona fide requirements for physically demanding occupations, 13–16 September 2000. York University, Toronto, Ont, Canada, pp 53–61Google Scholar
  9. Elbehairy AF, Ciavaglia CE, Webb KA, Guenette JA, Jensen D, Mourad SM, Neder JA, O’Donnell DE, Canadian Respiratory Research N (2015) Pulmonary gas exchange abnormalities in mild chronic obstructive pulmonary disease. implications for dyspnea and exercise intolerance. Am J Respir Crit Care Med 191(12):1384–1394CrossRefGoogle Scholar
  10. England SJ, Farhi LE (1976) Fluctuations in alveolar CO2 and in base excess during the menstrual cycle. Respir Physiol 26(2):157–161CrossRefGoogle Scholar
  11. Epstein Y, Yanovich R, Moran DS, Heled Y (2013) Physiological employment standards IV: integration of women in combat units physiological and medical considerations. Eur J Appl Physiol 2013:2673–2691CrossRefGoogle Scholar
  12. Guenette JA, Witt JD, McKenzie DC, Road JD, Sheel AW (2007) Respiratory mechanics during exercise in endurance-trained men and women. J Physiol 581(Pt 3):1309–1322CrossRefGoogle Scholar
  13. Harms CA, McClaran SR, Nickele GA, Pegelow DF, Nelson WB, Dempsey JA (1998) Exercise-induced arterial hypoxaemia in healthy young women. J Physiol 507(Pt 2):619–628CrossRefGoogle Scholar
  14. Henke KG, Sharratt M, Pegelow D, Dempsey JA (1988) Regulation of end-expiratory lung volume during exercise. J Appl Physiol 64(1):135–146CrossRefGoogle Scholar
  15. Hessemer V, Brück K (1985) Influence of menstrual cycle on thermoregulatory, metabolic, and heart rate responses to exercise at night. J Appl Physiol 59(6):1911–1917CrossRefGoogle Scholar
  16. Johnson BD, Weisman IM, Zeballos RJ, Beck KC (1999) Emerging concepts in the evaluation of ventilatory limitation during exercise: the exercise tidal flow-volume loop. Chest 116(2):488–503CrossRefGoogle Scholar
  17. Kenny GP, Groeller H, McGinn R, Flouris AD (2016) Age, human performance, and physical employment standards. Appl Physiol Nutr Metab 41(6 Suppl 2):S92–S107.  https://doi.org/10.1139/apnm-2015-0483 CrossRefGoogle Scholar
  18. Kilbride E, McLoughlin P, Gallagher CG, Harty HR (2003) Do gender differences exist in the ventilatory response to progressive exercise in males and females of average fitness? Eur J Appl Physiol 89(6):595–602CrossRefGoogle Scholar
  19. Lebrun CM, McKenzie DC, Prior JC, Taunton JE (1995) Effects of menstrual cycle phase on athletic performance. Med Sci Sports Exerc 27:437–444CrossRefGoogle Scholar
  20. MacNutt MJ, De Souza MJ, Tomczak SE, Homer JL, Sheel AW (2012) Resting and exercise ventilatory chemosensitivity across the menstrual cycle. J Appl Physiol 112(5):737–747CrossRefGoogle Scholar
  21. MacParland C, Krishnan B, Lobo J, Gallagher CG (1992) Effect of physical training on breathing pattern during progressive exercise. Respir Physiol 90:311–323CrossRefGoogle Scholar
  22. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J, Force AET (2005) Standardisation of spirometry. Eur Respir J 26(2):319–338CrossRefGoogle Scholar
  23. Patton JF, Kaszuba J, Mello RP, Reynolds KL (1991) Physiological responses to prolonged treadmill walking with external loads. Eur J Appl Physiol 63:89–93CrossRefGoogle Scholar
  24. Peoples GE, Lee DS, Notley SR, Taylor NA (2016) The effects of thoracic load carriage on maximal ambulatory work tolerance and acceptable work durations. Eur J Appl Physiol 116(3):635–646CrossRefGoogle Scholar
  25. Petersen A, Payne W, Phillips M, Netto K, Nichols D, Aisbett B (2010) Validity and relevance of the pack hike wildland firefighter work capacity test: a review. Ergo 53(10):1276–1285CrossRefGoogle Scholar
  26. Petersen SR, Anderson GS, Tipton MJ, Docherty D, Graham TE, Sharkey BJ, Taylor NA (2016) Towards best practice in physical and physiological employment standards. Appl Physiol Nutr Metab 41(6 Suppl 2):S47–S62CrossRefGoogle Scholar
  27. Phillips DB, Ehnes CM, Stickland MK, Petersen SR (2016a) The impact of thoracic load carriage up to 45 kg on the cardiopulmonary response to exercise. Eur J Appl Physiol 116(9):1725–1734CrossRefGoogle Scholar
  28. Phillips DB, Stickland MK, Lesser IA, Petersen SR (2016b) The effects of heavy load carriage on physiological responses to graded exercise. Eur J Appl Physiol 116(2):275–280CrossRefGoogle Scholar
  29. Phillips DB, Stickland MK, Petersen SR (2016c) Physiological and performance consequences of heavy thoracic load carriage in females. Appl Physiol Nutr Metab 41(7):741–748CrossRefGoogle Scholar
  30. Phillips DB, Stickland MK, Petersen SR (2016d) Ventilatory responses to prolonged exercise with heavy load carriage. Eur J Appl Physiol 116(1):19–27CrossRefGoogle Scholar
  31. Phillips DB, Ehnes CM, Welch BG, Lee LN, Simin I, Petersen SR (2018) Influence of work clothing on physiological responses and performance during treadmill exercise and the wildland firefighter pack test. Appl Ergon 68:313–318CrossRefGoogle Scholar
  32. Roberts D, Gebhardt DL, Gaskill SE, Roy TC, Sharp MA (2016) Current considerations related to physiological differences between the sexes and physical employment standards. Appl Physiol Nutr Metab 41(6 Suppl 2):S108–S120CrossRefGoogle Scholar
  33. Schaeffer MR, Mendonca CT, Levangie MC, Andersen RE, Taivassalo T, Jensen D (2014) Physiological mechanisms of sex differences in exertional dyspnoea: role of neural respiratory motor drive. Exp Physiol 99(2):427–441CrossRefGoogle Scholar
  34. Sheel AW, Romer LM (2012) Respiratory mechanics. Compr Physiol 2:1093–1142Google Scholar
  35. Stickland MK, Lindinger MI, Olfert IM, Heigenhauser GJ, Hopkins SR (2013) Pulmonary gas exchange and acid-base balance during exercise. Compr Physiol 3(2):693–739CrossRefGoogle Scholar
  36. Tan WC, Bourbeau J, Hernandez P, Chapman K, Cowie R, FitzGerald MJ, Aaron S, Marciniuk DD, Maltais F, O’Donnell DE, Goldstein R, Sin D, Investigators Ls (2011) Canadian prediction equations of spirometric lung function for Caucasian adults 20 to 90 years of age: results from the Canadian Obstructive Lung Disease (COLD) study and the Lung Health Canadian Environment (LHCE) study. Can Respir J 18(6):321–326CrossRefGoogle Scholar
  37. Wang L-Y, Cerny FJ (2004) Ventilatory response to exercise in simulated obesity by chest loading. Med Sci Sports Exerc:780–786Google Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Devin B. Phillips
    • 1
    • 2
    Email author
  • Cameron M. Ehnes
    • 1
  • Michael K. Stickland
    • 1
    • 2
    • 3
  • Stewart R. Petersen
    • 1
  1. 1.Faculty of Kinesiology, Sport, and RecreationUniversity of AlbertaEdmontonCanada
  2. 2.Division of Pulmonary Medicine, Department of MedicineUniversity of AlbertaEdmontonCanada
  3. 3.G. F. MacDonald Centre for Lung HealthCovenant HealthEdmontonCanada

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