Acute effect of stretching one leg on regional arterial stiffness in young men
- 544 Downloads
Our previous study demonstrated that a single bout of stretching exercises acutely reduced arterial stiffness. We hypothesized that this acute vascular response is due to regional mechanical stimulation of the peripheral arteries. To test this hypothesis, we examined the effect of a single bout of passive one leg stretching on arterial stiffness, comparing the stretched and the non-stretched leg in the same subject.
Twenty-five healthy young men (20.9 ± 0.3 years, 172.5 ± 1.4 cm, 64.1 ± 1.2 kg) volunteered for the study. Subjects underwent a passive calf stretching on one leg (six repetitions of 30-s static stretch with a 10-s recovery). Pulse wave velocity (PWV, an index of arterial stiffness), blood pressure (BP), and heart rate (HR) were measured before and immediately, 15, and 30 min after the stretching.
Femoral–ankle PWV (faPWV) in the stretched leg was significantly decreased from baseline (835.0 ± 15.9 cm/s) to immediately (802.9 ± 16.8 cm/s, P < 0.01) and 15 min (810.5 ± 16.0 cm/s, P < 0.01) after the stretching, despite no changes in systolic and diastolic BP, or HR. However, faPWV in the non-stretched leg was not significantly altered at any time. Brachial–ankle PWV (baPWV) also showed similar responses with faPWV, but this response was not significant. Additionally, the passive stretching did not alter carotid–femoral PWV (cfPWV).
These results suggest that mechanical stimulation to peripheral arteries as induced by static passive stretch may modulate arterial wall properties directly, rather than resulting in a systemic effect.
KeywordsPulse wave velocity Blood pressure Stretching Vasodilation
Analysis of variance
Brachial–ankle pulse wave velocity
Body mass index
Cardio-ankle vascular index
Carotid–femoral pulse wave velocity
Diastolic blood pressure
Femoral–ankle pulse wave velocity
Pulse wave velocity
Systolic blood pressure
This work was supported by Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan (KAKENHI: #26282199 for M. Iemitsu and 16K01746 for Y. Yamato).
Compliance with ethical standards
Conflict of interest
The authors declare no conflict of interest.
- Ashor AW, Lara J, Siervo M, Celis-Morales C, Mathers JC (2014) Effects of exercise modalities on arterial stiffness and wave reflection: a systematic review and meta-analysis of randomized controlled trials. PLoS One 9:e110034. doi: 10.1371/journal.pone.0110034 CrossRefPubMedPubMedCentralGoogle Scholar
- Fujie S, Hasegawa N, Sato K, Fujita S, Sanada K, Hamaoka T, Iemitsu M (2015) Aerobic exercise training-induced changes in serum adropin level are associated with reduced arterial stiffness in middle-aged and older adults. Am J Physiol Heart Circ Physiol 309:H1642–H1647. doi: 10.1152/ajpheart.00338.2015 PubMedGoogle Scholar
- Hotta K, Kamiya K, Shimizu R, Yokoyama M, Nakamura-Ogura M, Tabata M, Kamekawa D, Akiyama A, Kato M, Noda C, Matsunaga A, Masuda T (2013) Stretching exercises enhance vascular endothelial function and improve peripheral circulation in patients with acute myocardial infarction. Int Heart J 54:59–63CrossRefPubMedGoogle Scholar